AIMC Topic: Models, Biological

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Survival prognostic factors in patients with acute myeloid leukemia using machine learning techniques.

PloS one
This paper identifies prognosis factors for survival in patients with acute myeloid leukemia (AML) using machine learning techniques. We have integrated machine learning with feature selection methods and have compared their performances to identify ...

Deep Learning for Basal Cell Carcinoma Detection for Reflectance Confocal Microscopy.

The Journal of investigative dermatology
Basal cell carcinoma (BCC) is the most common skin cancer, with over 2 million cases diagnosed annually in the United States. Conventionally, BCC is diagnosed by naked eye examination and dermoscopy. Suspicious lesions are either removed or biopsied ...

Machine learning application for the prediction of SARS-CoV-2 infection using blood tests and chest radiograph.

Scientific reports
Triaging and prioritising patients for RT-PCR test had been essential in the management of COVID-19 in resource-scarce countries. In this study, we applied machine learning (ML) to the task of detection of SARS-CoV-2 infection using basic laboratory ...

A deep learning algorithm to translate and classify cardiac electrophysiology.

eLife
The development of induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) has been a critical in vitro advance in the study of patient-specific physiology, pathophysiology, and pharmacology. We designed a new deep learning multitask network ...

The structure-based cancer-related single amino acid variation prediction.

Scientific reports
Single amino acid variation (SAV) is an amino acid substitution of the protein sequence that can potentially influence the entire protein structure or function, as well as its binding affinity. Protein destabilization is related to diseases, includin...

Assessing the utility of deep neural networks in predicting postoperative surgical complications: a retrospective study.

The Lancet. Digital health
BACKGROUND: Early detection of postoperative complications, including organ failure, is pivotal in the initiation of targeted treatment strategies aimed at attenuating organ damage. In an era of increasing health-care costs and limited financial reso...

Long-term cancer survival prediction using multimodal deep learning.

Scientific reports
The age of precision medicine demands powerful computational techniques to handle high-dimensional patient data. We present MultiSurv, a multimodal deep learning method for long-term pan-cancer survival prediction. MultiSurv uses dedicated submodels ...

Deep learning to predict long-term mortality in patients requiring 7 days of mechanical ventilation.

PloS one
BACKGROUND: Among patients with acute respiratory failure requiring prolonged mechanical ventilation, tracheostomies are typically placed after approximately 7 to 10 days. Yet half of patients admitted to the intensive care unit receiving tracheostom...