AIMC Topic: Monte Carlo Method

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Predicting aptamer sequences that interact with target proteins using an aptamer-protein interaction classifier and a Monte Carlo tree search approach.

PloS one
Oligonucleotide-based aptamers, which have a three-dimensional structure with a single-stranded fragment, feature various characteristics with respect to size, toxicity, and permeability. Accordingly, aptamers are advantageous in terms of diagnosis a...

Non-line-of-Sight Imaging via Neural Transient Fields.

IEEE transactions on pattern analysis and machine intelligence
We present a neural modeling framework for non-line-of-sight (NLOS) imaging. Previous solutions have sought to explicitly recover the 3D geometry (e.g., as point clouds) or voxel density (e.g., within a pre-defined volume) of the hidden scene. In con...

Streamlined magnetic resonance fingerprinting: Fast whole-brain coverage with deep-learning based parameter estimation.

NeuroImage
Magnetic resonance fingerprinting (MRF) is a quantitative MRI (qMRI) framework that provides simultaneous estimates of multiple relaxation parameters as well as metrics of field inhomogeneity in a single acquisition. However, current challenges exist...

An assessment of contamination pickup on ground robotic vehicles for nuclear surveying application.

Journal of radiological protection : official journal of the Society for Radiological Protection
Ground robotic vehicles are often deployed to inspect areas where radioactive floor contamination is a prominent risk. However, the accuracy of detection could be adversely affected by enhanced radiation signal through self-contamination of the robot...

Advanced Monte Carlo simulations of emission tomography imaging systems with GATE.

Physics in medicine and biology
Built on top of the Geant4 toolkit, GATE is collaboratively developed for more than 15 years to design Monte Carlo simulations of nuclear-based imaging systems. It is, in particular, used by researchers and industrials to design, optimize, understand...

Breast glandularity and mean glandular dose assessment using a deep learning framework: Virtual patients study.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: Breast dosimetry in mammography is an important aspect of radioprotection since women are exposed periodically to ionizing radiation due to breast cancer screening programs. Mean glandular dose (MGD) is the standard quantity employed for the...

Evaluating advanced computing techniques for predicting breeding values in Harnali sheep.

Tropical animal health and production
Advanced computing techniques have been used by animal researchers to understand the intricate data structures for deriving the most reliable allusions of populations in order to conserve genetically superior animals. The present attempt was made to ...

Estimation of drug exposure by machine learning based on simulations from published pharmacokinetic models: The example of tacrolimus.

Pharmacological research
We previously demonstrated that Machine learning (ML) algorithms can accurately estimate drug area under the curve (AUC) of tacrolimus or mycophenolate mofetil (MMF) based on limited information, as well as or even better than maximum a posteriori Ba...

Radiation dose calculation in 3D heterogeneous media using artificial neural networks.

Medical physics
PURPOSE: External beam radiotherapy (EBRT) treatment planning requires a fast and accurate method of calculating the dose delivered by a clinical treatment plan. However, existing methods of calculating dose distributions have limitations. Monte Carl...

Calibrated uncertainty estimation for interpretable proton computed tomography image correction using Bayesian deep learning.

Physics in medicine and biology
Integrated-type proton computed tomography (pCT) measures proton stopping power ratio (SPR) images for proton therapy treatment planning, but its image quality is degraded due to noise and scatter. Although several correction methods have been propos...