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Neoadjuvant Therapy

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PANOPLY: Omics-Guided Drug Prioritization Method Tailored to an Individual Patient.

JCO clinical cancer informatics
PURPOSE: The majority of patients with cancer receive treatments that are minimally informed by omics data. We propose a precision medicine computational framework, PANOPLY (Precision Cancer Genomic Report: Single Sample Inventory), to identify and p...

[Neoadjuvant FOLFIRINOX for Unresectable Adenocarcinoma of the Pancreas - A Case Report].

Gan to kagaku ryoho. Cancer & chemotherapy
A 38-year-old male presented to our hospital with complaint of vomiting. A CT demonstrated a mass sized 42mm in the pancreatic head invading to the duodenum and a liver mass sized 15mm in the medial segment. Biopsy revealed adenocarcinoma. Due to liv...

[A Case of Carcinoma Associated with an Anal Fistula Repaired Using a Hatchet Flap after Neoadjuvant Chemoradiotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy
The patient was a 53-year-old man who complained of perianal pain. He had a 20-year history of an anal fistula. There was a 10 cm tumor with mucin-like discharge on the left side of the anus. His CEA level was high, at 7.3 ng/mL, and T2-weighted MRI ...

[Radical Resection of cT3a Gallbladder Cancer after Neoadjuvant Chemotherapy - A Case Report].

Gan to kagaku ryoho. Cancer & chemotherapy
We report a case of a radical resection of cT3a gallbladder cancer after neoadjuvant chemotherapy(NAC). A 68-year-old man was referred to our hospital with a chief complaint of right hypochondralgia.Imaging findings were consistent with acute cholecy...

Quantitative ultrasound assessment of breast tumor response to chemotherapy using a multi-parameter approach.

Oncotarget
PURPOSE: This study demonstrated the ability of quantitative ultrasound (QUS) parameters in providing an early prediction of tumor response to neoadjuvant chemotherapy (NAC) in patients with locally advanced breast cancer (LABC).

Robotic Assisted Extended Sleeve Lobectomy After Neoadjuvant Chemotherapy.

The Annals of thoracic surgery
A 61-year-old man had experienced an irritating cough for 1 month. He received a diagnosis of lung adenocarcinoma by bronchoscopy. Computed tomography showed a mass in the left hilum and mediastinal lymph node enlargement. After two cycles of neoadju...

[The Safety and Feasibility of Conversion Surgery for Initially Unresectable Pancreatic Cancer].

Gan to kagaku ryoho. Cancer & chemotherapy
BACKGROUND: By remarkable progress of chemotherapy for pancreatic cancer, we sometimes achieve resection of initially unresectable pancreatic cancer after chemotherapy. Otherwise, the safety and feasibility of radical pancreatic resection after chemo...