BACKGROUND: Next Generation Sequencing (NGS) technologies have revolutionized genomics data research over the last decades by facilitating high-throughput sequencing of genetic material such as RNA Sequencing (RNAseq). A significant challenge is to e...
DNA methylation change has been useful for cancer biomarker discovery, classification, and potential treatment development. So far, existing methods use either differentially methylated CpG sites or combined CpG sites, namely differentially methylate...
BACKGROUND: As the need for sharing genomic data grows, privacy issues and concerns, such as the ethics surrounding data sharing and disclosure of personal information, are raised.
Critical reviews in oncology/hematology
Aug 7, 2020
In recent years the concept of precision medicine has become a popular topic particularly in medical oncology. Besides the identification of new molecular prognostic and predictive biomarkers and the development of new targeted and immunotherapeutic ...
Exploring strategies to treat cancer has always been an aim of medical researchers. One of the available strategies is to use targeted therapy drugs to make the chromosomes in cancer cells unstable such that cell death can be induced, and the elimina...
Deep learning methods for digital pathology analysis are an effective way to address multiple clinical questions, from diagnosis to prediction of treatment outcomes. These methods have also been used to predict gene mutations from pathology images, b...
Research in medical imaging has yet to do to achieve precision oncology. Over the past 30 years, only the simplest imaging biomarkers (RECIST, SUV,…) have become widespread clinical tools. This may be due to our inability to accurately characterize t...
Journal of infection and public health
Aug 2, 2020
Cancer is a fatal illness often caused by genetic disorder aggregation and a variety of pathological changes. Cancerous cells are abnormal areas often growing in any part of human body that are life-threatening. Cancer also known as tumor must be qui...
Computer methods and programs in biomedicine
Aug 1, 2020
BACKGROUND AND OBJECTIVE: Multiple primary cancers significantly threat patient survivability. Predicting the survivability of patients with two cancers is challenging because its stochastic pattern relates with numerous variables.
Clinical pharmacology and therapeutics
Aug 1, 2020
The amount of "big" data generated in clinical oncology, whether from molecular, imaging, pharmacological, or biological origin, brings novel challenges. To mine efficiently this source of information, mathematical models able to produce predictive a...
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