In this review we summarise our recent efforts in trying to understand the role of heterogeneity in cancer progression by using neural networks to characterise different aspects of the mapping from a cancer cells genotype and environment to its pheno...
Nan fang yi ke da xue xue bao = Journal of Southern Medical University
Jan 20, 2026
Large language models (LLMs) are emerging artificial intelligence technologies with strong text and image processing capabilities, offering critical support for the intelligent transformation of healthcare and improving clinical efficiency and qualit...
Mathematical and computational modeling enables in silico testing of hypotheses, experimental design, and interventional strategies. However, building, sharing, and applying complex models require technical skills and software development knowledge t...
UNLABELLED: Precision oncology is becoming increasingly integral to clinical practice, demonstrating notable improvements in treatment outcomes. Whereas molecular data provide comprehensive insights, obtaining such data remains costly and time-consum...
Mathematical models have played a significant role in the development of current chemo- and radiotherapy treatment protocols. The widespread use of cytotoxic drugs has shaped the paradigm of uniformly administering a "maximum tolerated dose" to patie...
Cancer systems biology seeks to understand how cancer arises as a system of interconnected molecules, cells, and tissues, with the goal of understanding, predicting, and controlling the disease. In the last decade, the field has rapidly grown as adva...
This article discusses the specific advances made in precision oncology in 2025, in which we saw the approval of multiple new indications for known precision oncology agents and early promising data for novel agents that target either classical pathw...
BACKGROUND: Malignant tumors are a major global health crisis, causing 25% of deaths in China, with lung, liver, thyroid, breast, and colon cancers being the most common. Understanding the factors influencing hospitalization costs for these cancers i...
UNLABELLED: Recent studies have reported increases in early-onset cancer cases (diagnosed less than 50 years of age) and raised questions about whether the increase is related to earlier diagnosis from nonspecific medical tests as reflected by decrea...
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