Tyrosinase plays a central role in melanin biosynthesis, and its dysregulation has been implicated in the pathogenesis of various pigmentation disorders. The precise identification of tyrosinase inhibitory peptides (TIPs) is critical, as these bioact...
For most cancers, early diagnosis and intervention can significantly improve cure rates and patient survival. Consequently, achieving early and accurate cancer detection has always been a central focus in both medical practice and scientific research...
Early diagnosis of Alzheimer's disease (AD) requires blood biomarker tests sensitive to femtogram/mL concentrations. Graphene field-effect transistors (GFETs) are promising for this application, but suffer from device-to-device variability and requir...
Proceedings of the National Academy of Sciences of the United States of America
Oct 7, 2025
Understanding the computational principles of the brain and translating them into neuromorphic hardware and modern deep learning architectures is critical for advancing neuro-inspired AI (NeuroAI). Here, we develop an experimentally constrained, biop...
Image segmentation is an essential research field in image processing that has developed from traditional processing techniques to modern deep learning methods. In medical image processing, the primary goal of the segmentation process is to segment o...
Artificial intelligence (AI) algorithms have demonstrated remarkable efficiency in analyzing 12-lead clinical electrocardiogram (ECG) signals. This has sparked interest in leveraging cost-effective and user-friendly smart devices based on single-lead...
Parkinson's disease (PD) is a progressive neurodegenerative disorder that remained challenging for proper diagnosis in its early stages due to its heterogeneous symptom presentation and overlapping clinical features. Consequently, there is no consens...
To reduce the pressure on public health services caused by the aging population, nursing homes need to predict disease risks for the elderly periodically. To improve the disease risks predicting ability of nursing homes, we designed Anston (An Attent...
BACKGROUND: Early-stage diagnosis of laryngeal cancer significantly improves patient survival and quality of life. However, the scarcity of specialists in low-resource settings hinders the timely review of flexible nasopharyngoscopy (FNS) videos, whi...
Journal of computer-aided molecular design
Oct 7, 2025
Drug discovery relies on the ability to predict drug-target affinity (DTA), which allows for the efficient identification of drug candidates for certain protein targets. Scalability, accuracy, and interpretability are issues that traditional methods ...
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