For quantitative neuroimaging studies using multi-echo gradient echo (mGRE) images, additional T-weighted magnetization prepared rapid gradient echo (MPRAGE) images are often acquired to supplement the insufficient morphometric information of mGRE fo...
Dedicated brain positron emission tomography (PET) devices can provide higher-resolution images with much lower doses compared to conventional whole-body PET systems, which is important to support PET neuroimaging and particularly useful for the diag...
Detailed whole brain segmentation is an essential quantitative technique in medical image analysis, which provides a non-invasive way of measuring brain regions from a clinical acquired structural magnetic resonance imaging (MRI). Recently, deep conv...
Hippocampus segmentation plays a significant role in mental disease diagnoses, such as Alzheimer's disease, epilepsy, and so on. Patch-based multi-atlas segmentation (PBMAS) approach is a popular method for hippocampus segmentation and has achieved a...
Combining neuroimaging and clinical information for diagnosis, as for example behavioral tasks and genetics characteristics, is potentially beneficial but presents challenges in terms of finding the best data representation for the different sources ...
IEEE reviews in biomedical engineering
Mar 12, 2019
Dementia is a chronic and degenerative condition affecting millions globally. The care of patients with dementia presents an ever-continuing challenge to healthcare systems in the 21st century. Medical and health sciences have generated unprecedented...
Neuromelanin sensitive magnetic resonance imaging (NMS-MRI) has been crucial in identifying abnormalities in the substantia nigra pars compacta (SNc) in Parkinson's disease (PD) as PD is characterized by loss of dopaminergic neurons in the SNc. Curre...
Annals of clinical and translational neurology
Mar 4, 2019
OBJECTIVE: Clot characteristics can provide information on the cause of cerebral artery occlusion and may guide acute revascularization and secondary prevention strategies. We developed a rapid automated clot analysis system using machine learning (M...
AJNR. American journal of neuroradiology
Feb 28, 2019
BACKGROUND AND PURPOSE: MR imaging-based modeling of tumor cell density can substantially improve targeted treatment of glioblastoma. Unfortunately, interpatient variability limits the predictive ability of many modeling approaches. We present a tran...
Time-dependent data collected in studies of Alzheimer's disease usually has missing and irregularly sampled data points. For this reason time series methods which assume regular sampling cannot be applied directly to the data without a pre-processing...