AIMC Topic: NF-E2-Related Factor 2

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RASPELD to Perform High-End Screening in an Academic Environment toward the Development of Cancer Therapeutics.

ChemMedChem Aug 23, 2018
The identification of compounds for dissecting biological functions and the development of novel drug molecules are central tasks that often require screening campaigns. However, the required architecture is cost- and time-intensive. Herein we descri...
ErbB Receptors Protein Kinase Inhibitors Biological Assay Ligands Education, Graduate Kelch-Like ECH-Associated Protein 1 NF-E2-Related Factor 2 Small Molecule Libraries Dose-Response Relationship, Drug Robotics Antineoplastic Agents Mutation Protein Binding Drug Evaluation, Preclinical Humans
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Hericium erinaceus Inhibits TNF-α-Induced Angiogenesis and ROS Generation through Suppression of MMP-9/NF-κB Signaling and Activation of Nrf2-Mediated Antioxidant Genes in Human EA.hy926 Endothelial Cells.

Oxidative medicine and cellular longevity Dec 28, 2015
Hericium erinaceus (HE) is an edible mushroom that has been shown to exhibit anticancer and anti-inflammatory activities. We investigated the antiangiogenic and antioxidant potentials of ethanol extracts of HE in human endothelial (EA.hy926) cells up...
Neovascularization, Pathologic Heme Oxygenase-1 Matrix Metalloproteinase 9 Intercellular Adhesion Molecule-1 Endothelial Cells NF-E2-Related Factor 2 Glutathione Basidiomycota Angiogenesis Inhibitors Reactive Oxygen Species NF-kappa B Anti-Inflammatory Agents Inflammation Signal Transduction Antioxidants Angiogenesis Inducing Agents Humans Tumor Necrosis Factor-alpha
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Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.

World journal of gastroenterology Dec 21, 2017
AIM: To investigate whether morin can reduce hepatic fibrosis by activating the NF-E2-related factor 2 (Nrf2) signaling pathway.
Rats, Sprague-Dawley NF-E2-Related Factor 2 Disease Models, Animal Weight Loss Carbon Tetrachloride Flavonoids Liver Cirrhosis Oxidative Stress Liver Function Tests Signal Transduction Antioxidants Liver Animals Humans Rats Protective Agents Male
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[Effects of hydrogen rich water on the expression of Nrf 2 and the oxidative stress in rats with traumatic brain injury].

Zhonghua wei zhong bing ji jiu yi xue Nov 1, 2015
OBJECTIVE: To investigate the effects of hydrogen rich water on the expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and oxidative stress in rats with traumatic brain injury (TBI).
Animals Male Water Hydrogen Oxidative Stress NF-E2-Related Factor 2 Brain Injuries Rats Brain Random Allocation Rats, Sprague-Dawley
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