Aging clinical and experimental research
Jul 9, 2025
BACKGROUND: Sarcopenic obesity (SO) has a higher risk of adverse health events compared to having obesity or sarcopenia alone due to the dual burden of both muscle loss and fat gain. The prevalence of SO is progressively increasing as the population ...
BACKGROUND: To investigate the association between the Dietary Inflammatory Index (DII), biological aging, and the staging and mortality of cardiovascular-kidney-metabolic (CKM) syndrome.
BACKGROUND: This study employed representative data from the U.S. and China to delve into the correlation among migraine prevalence, the triglyceride‒glucose index, a marker of insulin resistance, and the composite indicator of obesity.
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a major global public health concern, and early screening and identification of high-risk populations are critical for reducing the disease burden. Although several studies have explored the...
Cardiometabolic Multimorbidity (CMM) has emerged as one of the primary threats to human health globally due to its high incidence, disability, and mortality rates. Accurate identification of CMM patterns is crucial for CMM classification and health m...
BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is a prevalent respiratory condition often accompanied by depression, which exacerbates disease burden and impairs quality of life. Early identification of depression risk in COPD patients rema...
Sarcopenia, characterized by progressive loss of muscle mass and function, is a growing public health concern. The ZJU index, a novel metabolic marker, integrates lipid metabolism and glucose regulation parameters. While its association with metaboli...
BMC medical informatics and decision making
Jul 1, 2025
OBJECTIVE: Using 2005-2018 NHANES data, this study examined the association between the visceral fat metabolism score (METS-VF) and heart failure (HF) prevalence in U.S. adults, leveraging machine learning (LightGBM/XGBoost) and SHAP for classficatio...
BACKGROUND: Brominated flame retardants (BFRs) are classified as important endocrine disruptors and persistent organic pollutants; nevertheless, there is no comprehensive investigation to evaluate the association between BFRs and hyperuricemia, and t...
BACKGROUND: Chronic Kidney Disease (CKD) affects approximately 697.5 million people worldwide. Volatile organic compounds (VOCs) are emerging as potential risk factors, but their complex relationships with CKD may be underestimated by traditional lin...
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