AIMC Topic: Oxidation-Reduction
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Development of super-atmospheric oxidation chamber for orthodox tea processing and its validation through neural network approach.
Journal of the science of food and agriculture
Mar 12, 2019
BACKGROUND: Orthodox tea is known for its distinct aroma and superior quality. However, the oxidation step that is most crucial for developing these attributes needs precise control and is also time consuming. In the present study, a super-atmospheri...
Dry olive leaf extract attenuates DNA damage induced by estradiol and diethylstilbestrol in human peripheral blood cells in vitro.
Mutation research. Genetic toxicology and environmental mutagenesis
Dec 21, 2018
Phenolic groups of steroidal or nonsteroidal estrogens can redox cycle, leading to oxidative stress, where creation of reactive oxygen species are recognized as the main mechanism of their DNA damage properties. Dry olive (Olea europaea L.) leaf extr...
Comet Assay
Antioxidants
Diethylstilbestrol
Plant Extracts
Reactive Oxygen Species
Adult
Dose-Response Relationship, Drug
Humans
Estrogen Antagonists
Plant Leaves
Male
Female
Oxidation-Reduction
Free Radical Scavengers
Oxidative Stress
Young Adult
Drug Evaluation, Preclinical
DNA Damage
Estradiol
Olea
Blood Cells
Validation of a UPLC-PDA method to study the content and stability of 5-chloro 8-hydroxyquinoline and 5,7-dichloro 8-hydroxyquinoline in medicated feed used in swine farming.
Journal of pharmaceutical and biomedical analysis
Dec 21, 2018
A new, rapid, simple and specific method to determine 5-chloro 8-hydroxyquinoline (5-HQ) and 5,7-dichloro 8-hydroxyquinoline (5,7-HQ) stability in swine feed was optimized and validated. A system consisting of an ACQUITY UPLC BEH C column (1.7 μm, 2....
Bimolecular Nucleophilic Substitution Reactions: Predictive Models for Rate Constants and Molecular Reaction Pairs Analysis.
Molecular informatics
Nov 23, 2018
Here, we report the data visualization, analysis and modeling for a large set of 4830 S 2 reactions the rate constant of which (logk) was measured at different experimental conditions (solvent, temperature). The reactions were encoded by one single m...
Prediction of methionine oxidation risk in monoclonal antibodies using a machine learning method.
mAbs
Sep 25, 2018
Monoclonal antibodies (mAbs) have become a major class of protein therapeutics that target a spectrum of diseases ranging from cancers to infectious diseases. Similar to any protein molecule, mAbs are susceptible to chemical modifications during the ...
Light-Driven Micro/Nanomotor for Promising Biomedical Tools: Principle, Challenge, and Prospect.
Accounts of chemical research
Sep 4, 2018
A micro/nanomotor (MNM), as miniaturized machinery, can potentially bridge the application gap between the traditional macroscale motor and the molecular motor to manipulate materials at the cellular scale. The fascinating biomedical potential applic...
Exploring the phenolic profile, antioxidant, antidiabetic and anti-hemolytic potential of Prunus avium vegetal parts.
Food research international (Ottawa, Ont.)
Sep 2, 2018
The aim of the present work was to evaluate the phenolic profile of leaves, stems and flowers of P. avium and their biological potential. For this purpose, two extracts of each matrix (hydroethanolic and infusion) were prepared. A total of twenty-six...
SVM-SulfoSite: A support vector machine based predictor for sulfenylation sites.
Scientific reports
Jul 26, 2018
Protein S-sulfenylation, which results from oxidation of free thiols on cysteine residues, has recently emerged as an important post-translational modification that regulates the structure and function of proteins involved in a variety of physiologic...
Multiclassification Prediction of Enzymatic Reactions for Oxidoreductases and Hydrolases Using Reaction Fingerprints and Machine Learning Methods.
Journal of chemical information and modeling
May 21, 2018
Drug metabolism is a complex procedure in the human body, including a series of enzymatically catalyzed reactions. However, it is costly and time consuming to investigate drug metabolism experimentally; computational methods are hence developed to pr...
Comparison of Selected Parameters of Redox Homeostasis in Patients with Ataxia-Telangiectasia and Nijmegen Breakage Syndrome.
Oxidative medicine and cellular longevity
Dec 31, 2017
This study compared the antioxidant status and major lipophilic antioxidants in patients with ataxia-telangiectasia (AT) and Nijmegen breakage syndrome (NBS). Total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI), a...
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