Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy
Jan 28, 2022
Globally with over 10 million deaths per year, cancer is the most transversal disease across countries, cultures, and ethnicities, affecting both developed and developing regions. Tumorigenesis is dynamically altered by distinct events and can be let...
Many methodologies are used to predict the genetic merit in animals and plants, but some of them require priori assumptions that may increase the complexity of the model. Artificial neural network (ANN) has advantage to not require priori assumptions...
Completing the genotype-to-phenotype map requires rigorous measurement of the entire multivariate organismal phenotype. However, phenotyping on a large scale is not feasible for many kinds of traits, resulting in missing data that can also cause prob...
In recent years, exome sequencing (ES) has shown great utility in the diagnoses of Mendelian disorders. However, after rigorous filtering, a typical ES analysis still involves the interpretation of hundreds of variants, which greatly hinders the rapi...
Journal of the mechanical behavior of biomedical materials
Jan 19, 2022
Although cellular elastic property (CEP, also known as cellular elastic modulus) has been frequently reported as a biomarker to distinguish some cancerous cells from their benign counterparts, it cannot be adopted as a universal hallmark to be applie...
Advances in magnetic resonance imaging have shown how individual differences in the structure and function of the human brain relate to health and cognition. The relationship between individual differences and the levels of neuro-metabolites, however...
Identification of cell phenotypic states within heterogeneous populations, along with elucidation of their switching dynamics, is a central challenge in modern biology. Conventional single-cell analysis methods typically provide only indirect, static...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Dec 27, 2021
BACKGROUND AND PURPOSE: The preoperative lymph node (LN) status is important for the treatment of colorectal cancer (CRC). Here, we established and validated a deep learning (DPL) model for predicting lymph node metastasis (LNM) in CRC.
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