Computer methods and programs in biomedicine
Jul 18, 2017
BACKGROUND AND OBJECTIVE: The differentiation of mild cognitive impairment (MCI), which is the prodromal stage of Alzheimer's disease (AD), from normal control (NC) is important as the recent research emphasis on early pre-clinical stage for possible...
Identifying individuals destined to develop Alzheimer's dementia within time frames acceptable for clinical trials constitutes an important challenge to design studies to test emerging disease-modifying therapies. Although amyloid-β protein is the co...
A variety of compartment models are used for the quantitative analysis of dynamic positron emission tomography (PET) data. Traditionally, these models use an iterative fitting (IF) method to find the least squares between the measured and calculated ...
Computational and mathematical methods in medicine
Apr 3, 2017
The PET and CT fusion images, combining the anatomical and functional information, have important clinical meaning. This paper proposes a novel fusion framework based on adaptive pulse-coupled neural networks (PCNNs) in nonsubsampled contourlet trans...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Feb 7, 2017
Alzheimer's disease (AD) is the most common type of dementia and will be an increasing health problem in society as the population ages. Mild cognitive impairment (MCI) is considered to be a prodromal stage of AD. The ability to identify subjects wit...
Computational and mathematical methods in medicine
Dec 14, 2016
. Similar to PET, absolute quantitative imaging is becoming available in commercial SPECT/CT devices. This study's goal was to assess quantitative accuracy of activity recovery as a function of image reconstruction parameters and count statistics in ...
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention
Oct 2, 2016
Effectively utilizing incomplete multi-modality data for diagnosis of Alzheimer's disease (AD) is still an area of active research. Several multi-view learning methods have recently been developed to deal with missing data, with each view correspondi...
Accurate and reliable tumour delineation on positron emission tomography (PET) is crucial for radiotherapy treatment planning. PET automatic segmentation (PET-AS) eliminates intra- and interobserver variability, but there is currently no consensus on...
IEEE transactions on bio-medical engineering
May 12, 2016
OBJECTIVE: To obtain high-quality positron emission tomography (PET) image with low-dose tracer injection, this study attempts to predict the standard-dose PET (S-PET) image from both its low-dose PET (L-PET) counterpart and corresponding magnetic re...
Brain amyloid burden may be quantitatively assessed from positron emission tomography imaging using standardised uptake value ratios. Using these ratios as an adjunct to visual image assessment has been shown to improve inter-reader reliability, howe...