Application of kinetic modeling (KM) on a voxel level in dynamic PET images frequently suffers from high levels of noise, drastically reducing the precision of parametric image analysis. In this paper, we investigate the use of machine learning and a...
PURPOSE: To apply an artificial neural network (ANN) for fast and robust quantification of the oxygen extraction fraction (OEF) from a combined QSM and quantitative BOLD analysis of gradient echo data and to compare the ANN to a traditional quasi-New...
European journal of nuclear medicine and molecular imaging
Jul 1, 2019
OBJECTIVE: Quantitative PET/MR imaging is challenged by the accuracy of synthetic CT (sCT) generation from MR images. Deep learning-based algorithms have recently gained momentum for a number of medical image analysis applications. In this work, a no...
The differential diagnosis of primary central nervous system lymphoma from glioblastoma multiforme (GBM) is essential due to the difference in treatment strategies. This study retrospectively reviewed 77 patients (24 with lymphoma and 53 with GBM) to...
Journal of the American College of Radiology : JACR
Jun 26, 2019
The advent of artificial intelligence (AI) promises to have a transformational impact on quality in medicine, including in radiology. However, experience has shown that quality tools alone are often not sufficient to bring about consistent excellent ...
The differentiation of dementia with Lewy bodies (DLB) from Alzheimer's disease (AD) using brain perfusion single photon emission tomography is important but is challenging because these conditions exhibit typical features. The cingulate island sign ...
PURPOSE: Our goal was to use a generative adversarial network (GAN) with feature matching and task-specific perceptual loss to synthesize standard-dose amyloid Positron emission tomography (PET) images of high quality and including accurate pathologi...
PET images often suffer poor signal-to-noise ratio (SNR). Our objective is to improve the SNR of PET images using a deep neural network (DNN) model and MRI images without requiring any higher SNR PET images in training. Our proposed DNN model consist...
Clinical cancer research : an official journal of the American Association for Cancer Research
Apr 22, 2019
PURPOSE: Tumors are continuously evolving biological systems, and medical imaging is uniquely positioned to monitor changes throughout treatment. Although qualitatively tracking lesions over space and time may be trivial, the development of clinicall...
BACKGROUND: Recent deep learning models have shown remarkable accuracy for the diagnostic classification. However, they have limitations in clinical application due to the gap between the training cohorts and real-world data. We aimed to develop a mo...
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