Disturbed calcium homeostasis in patients with sepsis is associated with poor prognosis; however, its dynamic pattern and clinical significance remain unclear. This study aimed to establish an early warning system for calcium homeostasis in sepsis by...
BACKGROUND: Traumatic brain injury (TBI) is among the most prevalent causes of emergency department visits globally. TBI leads to high morbidity and mortality rates, which poses a noteworthy burden on the medical system regarding both patients and ec...
BACKGROUND: Cardio-renal syndrome (CRS), characterized by multi-organ interaction, is frequently overlooked in clinical practice. It poses significant challenges in treatment, leading to poor long-term prognosis and substantial economic burden on pat...
The study investigates the correlation between CD3 T-cell expression levels and cervical cancer (CC) while developing a magnetic resonance (MR) imaging-based radiomics model for preoperative prediction of CD3 T-cell expression levels. Prognostic corr...
The combination of chemotherapy can enhance the efficacy of immune checkpoint inhibitors (ICIs), but requires precise patient stratification and biomarker screening. Cytokines influence immunotherapy outcomes, and multiplex cytokine profiling aids in...
BACKGROUND: Ferroptosis and disulfidptosis are newly discovered forms of regulated cell death that play critical roles in cancer progression, metabolism, and immune evasion. However, their interplay and combined influence on colorectal cancer (CRC) p...
Chloride channel accessory 1 (CLCA1) is considered a potential prognostic biomarker for colon adenocarcinoma (COAD). The objective of this research was to develop two pathomics models to predict CLCA1 expression from hematoxylin-eosin (H&E) stained p...
Cancer imaging : the official publication of the International Cancer Imaging Society
Jul 18, 2025
BACKGROUND: While the TNM staging system provides valuable insights into the extent of disease, predicting postoperative progression in early-stage non-small cell lung cancer (NSCLC) remains a significant challenge. An effective bioimaging prognostic...
DNA metabolism genes play pivotal roles in the regulation of cellular processes that contribute to cancer progression, immune modulation, and therapeutic response in prostate cancer (PC). Understanding the mechanisms by which these genes influence th...
INTRODUCTION: Adverse prognostic events (APE) of neurosyphilis include ongoing syphilitic meningitis, meningovascular syphilis, parenchymatous neurosyphilis and death. Its complexity and rarity have the potential to result in the underestimated true ...
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