AIMC Topic: Prognosis

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Potential Prognostic Markers in the Heart Rate Variability Features for Early Diagnosis of Sepsis in the Pediatric Intensive Care Unit using Convolutional Neural Network Classifiers.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Blood infection due to different circumstances could immediately develop to an extreme body reaction that leads to a serious life-threatening condition, called Sepsis. Currently, therapeutic protocols through timely antibiotic resuscitation strategie...

Predicting complications of diabetes mellitus using advanced machine learning algorithms.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: We sought to predict if patients with type 2 diabetes mellitus (DM2) would develop 10 selected complications. Accurate prediction of complications could help with more targeted measures that would prevent or slow down their development.

Imputing missing RNA-sequencing data from DNA methylation by using a transfer learning-based neural network.

GigaScience
BACKGROUND: Gene expression plays a key intermediate role in linking molecular features at the DNA level and phenotype. However, owing to various limitations in experiments, the RNA-seq data are missing in many samples while there exist high-quality ...

Dr. Agent: Clinical predictive model via mimicked second opinions.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Prediction of disease phenotypes and their outcomes is a difficult task. In practice, patients routinely seek second opinions from multiple clinical experts for complex disease diagnosis. Our objective is to mimic such a practice of seekin...

Unsupervised machine learning and prognostic factors of survival in chronic lymphocytic leukemia.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Unsupervised machine learning approaches hold promise for large-scale clinical data. However, the heterogeneity of clinical data raises new methodological challenges in feature selection, choosing a distance metric that captures biological...

Spinal Stenosis Grading in Magnetic Resonance Imaging Using Deep Convolutional Neural Networks.

Spine
STUDY DESIGN: Retrospective magnetic resonance imaging grading with comparison between experts and deep convolutional neural networks (CNNs).

Deep-Learning-Based Characterization of Tumor-Infiltrating Lymphocytes in Breast Cancers From Histopathology Images and Multiomics Data.

JCO clinical cancer informatics
PURPOSE: Tumor-infiltrating lymphocytes (TILs) and their spatial characterizations on whole-slide images (WSIs) of histopathology sections have become crucial in diagnosis, prognosis, and treatment response prediction for different cancers. However, ...

Automated interpretation of the coronary angioscopy with deep convolutional neural networks.

Open heart
BACKGROUND: Coronary angioscopy (CAS) is a useful modality to assess atherosclerotic changes, but interpretation of the images requires expert knowledge. Deep convolutional neural networks (DCNN) can be used for diagnostic prediction and image synthe...

EXpectation Propagation LOgistic REgRession on permissioned blockCHAIN (ExplorerChain): decentralized online healthcare/genomics predictive model learning.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Predicting patient outcomes using healthcare/genomics data is an increasingly popular/important area. However, some diseases are rare and require data from multiple institutions to construct generalizable models. To address institutional d...