PURPOSE: To develop and evaluate a patch-based convolutional neural network (CNN) to generate synthetic computed tomography (sCT) images for magnetic resonance (MR)-only workflow for radiotherapy of head and neck tumors. A patch-based deep learning m...
OBJECTIVES: The conceptus dose during diagnostic imaging procedures for pregnant patients raises health concerns owing to the high radiosensitivity of the developing embryo/fetus. The aim of this work is to develop a methodology for automated constru...
An accurate prediction of achievable dose distribution on a patient specific basis would greatly improve IMRT/VMAT planning in both efficiency and quality. Recently machine learning techniques have been proposed for IMRT dose prediction based on pati...
PURPOSE: To investigate the treatment response prediction feasibility and accuracy of an integrated model combining computed tomography (CT) radiomic features and dosimetric parameters for patients with esophageal cancer (EC) who underwent concurrent...
Stochastic frontier analysis (SFA) is used as a novel knowledge-based technique in order to develop a predictive model of dosimetric features from significant geometric parameters describing a patient morphology. 406 patients treated with VMAT for pr...
Medical dosimetry : official journal of the American Association of Medical Dosimetrists
Apr 1, 2019
INTRODUCTION: Cone-beam CT (CBCT) image quality is important for its quantitative analysis in adaptive radiation therapy. However, due to severe artifacts, the CBCTs are primarily used for verifying patient setup only so far. We have developed a lear...
Medical dosimetry : official journal of the American Association of Medical Dosimetrists
Mar 1, 2019
The purpose of this study was to evaluate and compare the dosimetric effects of HyperArc-based stereotactic radiosurgery (SRS) and a robotic radiosurgery system-based planning using CyberKnife for multiple cranial metastases. In total, 11 cancer pati...
The cytokinesis-block micronucleus (CBMN) assay has become a fully-validated and standardized method for radiation biodosimetry. The assay is typically performed using microscopy, which is labor intensive, time consuming and impractical after a large...
PURPOSE: Few features characterizing the dosimetric properties of the patients are included in currently available dose-volume histogram (DVH) prediction models, making it intractable to build a correlative relationship between the input and output p...
PURPOSE: This study aimed to evaluate the feasibility of using a single-institution, knowledge-based planning (KBP) model as a dosimetric plan quality control (QC) for multi-institutional clinical trials. The efficacy of this QC tool was retrospectiv...
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