AIMC Topic: Radiometry
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Stochastic frontier analysis as knowledge-based model to improve sparing of organs-at-risk for VMAT-treated prostate cancer.
Physics in medicine and biology
Apr 8, 2019
Stochastic frontier analysis (SFA) is used as a novel knowledge-based technique in order to develop a predictive model of dosimetric features from significant geometric parameters describing a patient morphology. 406 patients treated with VMAT for pr...
Dosimetric study on learning-based cone-beam CT correction in adaptive radiation therapy.
Medical dosimetry : official journal of the American Association of Medical Dosimetrists
Apr 1, 2019
INTRODUCTION: Cone-beam CT (CBCT) image quality is important for its quantitative analysis in adaptive radiation therapy. However, due to severe artifacts, the CBCTs are primarily used for verifying patient setup only so far. We have developed a lear...
Automated noncoplanar treatment planning strategy in stereotactic radiosurgery of multiple cranial metastases: HyperArc and CyberKnife dose distributions.
Medical dosimetry : official journal of the American Association of Medical Dosimetrists
Mar 1, 2019
The purpose of this study was to evaluate and compare the dosimetric effects of HyperArc-based stereotactic radiosurgery (SRS) and a robotic radiosurgery system-based planning using CyberKnife for multiple cranial metastases. In total, 11 cancer pati...
Automated Triage Radiation Biodosimetry: Integrating Imaging Flow Cytometry with High-Throughput Robotics to Perform the Cytokinesis-Block Micronucleus Assay.
Radiation research
Feb 19, 2019
The cytokinesis-block micronucleus (CBMN) assay has become a fully-validated and standardized method for radiation biodosimetry. The assay is typically performed using microscopy, which is labor intensive, time consuming and impractical after a large...
Dosimetric features-driven machine learning model for DVH prediction in VMAT treatment planning.
Medical physics
Jan 2, 2019
PURPOSE: Few features characterizing the dosimetric properties of the patients are included in currently available dose-volume histogram (DVH) prediction models, making it intractable to build a correlative relationship between the input and output p...
Multi-Institutional Validation of a Knowledge-Based Planning Model for Patients Enrolled in RTOG 0617: Implications for Plan Quality Controls in Cooperative Group Trials.
Practical radiation oncology
Dec 15, 2018
PURPOSE: This study aimed to evaluate the feasibility of using a single-institution, knowledge-based planning (KBP) model as a dosimetric plan quality control (QC) for multi-institutional clinical trials. The efficacy of this QC tool was retrospectiv...
Personalized Models for Injected Activity Levels in SPECT Myocardial Perfusion Imaging.
IEEE transactions on medical imaging
Dec 6, 2018
We propose a patient-specific ("personalized") approach for tailoring the injected activities to individual patients in order to achieve dose reduction in SPECT-myocardial perfusion imaging (MPI). First, we develop a strategy to determine the minimum...
Feasibility of photon beam profile deconvolution using a neural network.
Medical physics
Oct 25, 2018
PURPOSE: Ionization chambers are the detectors of choice for photon beam profile scanning. However, they introduce significant volume averaging effect (VAE) that can artificially broaden the penumbra width by 2-3 mm. The purpose of this study was to ...
Assessment of specific versus combined purpose knowledge based models in prostate radiotherapy.
Journal of applied clinical medical physics
Oct 19, 2018
Knowledge-based planning (KBP) can be used to improve plan quality, planning speed, and reduce the inter-patient plan variability. KPB may also identify and reduce systematic variations in VMAT plans, something very important in multi-institutional c...
Temporal separation of Cerenkov radiation and scintillation using artificial neural networks in Clinical LINACs.
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Oct 10, 2018
The irradiation of scintillator-fiber optic dosimeters by clinical LINACs results in the measurement of scintillation and Cerenkov radiation. In scintillator-fiber optic dosimetry, the scintillation and Cerenkov radiation responses are separated to d...
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