BACKGROUND: This longitudinal study explored the utility of machine learning (ML) methodology in predicting the trajectory of severity of substance use from childhood to thirty years of age using a set of psychological and health characteristics.
Machine learning has increasingly been applied to classification of schizophrenia in neuroimaging research. However, direct replication studies and studies seeking to investigate generalizability are scarce. To address these issues, we assessed withi...
OBJECTIVES: Current models for patient risk prediction rely on practitioner expertise and domain knowledge. This study presents a deep learning model-a type of machine learning that does not require human inputs-to analyze complex clinical and financ...
Computational and mathematical methods in medicine
Oct 1, 2019
In this work, an ontology-based model for AI-assisted medicine side-effect (SE) prediction is developed, where three main components, including the drug model, the treatment model, and the AI-assisted prediction model, of the proposed model are prese...
International journal of molecular sciences
Sep 30, 2019
The constitutive androstane receptor (CAR) plays pivotal roles in drug-induced liver injury through the transcriptional regulation of drug-metabolizing enzymes and transporters. Thus, identifying regulatory factors for CAR activation is important for...
BACKGROUND: Current modes of identifying alcohol misuse in hospitalized patients rely on self-report questionnaires and diagnostic codes that have limitations, including low sensitivity. Information in the clinical notes of the electronic health reco...
International journal of molecular sciences
Sep 28, 2019
The ability to predict the skin sensitization potential of small organic molecules is of high importance to the development and safe application of cosmetics, drugs and pesticides. One of the most widely accepted methods for predicting this hazard is...
Computer methods and programs in biomedicine
Sep 27, 2019
BACKGROUND AND OBJECTIVES: The retinal fundus contains intricate vascular trees, some of which are mutually intersected and overlapped. The intersection and overlapping of retinal vessels represent vascular junctions (i.e. bifurcation and crossover) ...
Computer methods and programs in biomedicine
Sep 27, 2019
BACKGROUND AND OBJECTIVE: In recent years, several automatic sleep stage classification methods based on convolutional neural networks (CNN) by learning hierarchical feature representation automatically from raw EEG data have been proposed. However, ...
PURPOSE: Prompt diagnosis and quantitation of pneumothorax impact decisions pertaining to patient management. The purpose of our study was to develop and evaluate the accuracy of a deep learning (DL)-based image classification program for detection o...
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