AIMC Topic: Reproducibility of Results

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Carbon dots-modified chitosan based electrochemical biosensing platform for detection of vitamin D.

International journal of biological macromolecules Dec 21, 2017
Here in, a carbon dots (CDs)-modified chitosan (CH) based biosensing platform was fabricated for vitamin D detection. Carbon dots were synthesized through microwave pyrolysis method, and characterized with transmission electron microscopy, Raman spec...
Quantum Dots Electrochemical Techniques Nanocomposites Citric Acid Microscopy, Atomic Force Dielectric Spectroscopy Biosensing Techniques Vitamin D Carbon Chitosan Reproducibility of Results
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Prognostic Implications of Magnetic Resonance-Derived Quantification in Asymptomatic Patients With Organic Mitral Regurgitation: Comparison With Doppler Echocardiography-Derived Integrative Approach.

Circulation Dec 21, 2017
BACKGROUND: Magnetic resonance imaging (MRI) is an accurate method for the quantitative assessment of organic mitral regurgitation (OMR). The aim of the present study was to compare the discriminative power of MRI quantification and the recommended D...
Male Middle Aged Severity of Illness Index ROC Curve Female Reproducibility of Results Aged Sensitivity and Specificity Proportional Hazards Models Kaplan-Meier Estimate Echocardiography, Doppler Magnetic Resonance Imaging Area Under Curve Mitral Valve Mitral Valve Insufficiency Humans Prognosis
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Metal-organic framework UiO-66 for rapid dispersive solid phase extraction of neonicotinoid insecticides in water samples.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Dec 21, 2017
UIO-66 crystals were explored for the first time to adsorb neonicotinoid insecticides in environmental water samples. HPLC coupled with tandem MS was used for quantification and determination of neonicotinoid insecticides. UiO-66 crystals was success...
Insecticides Adsorption Solid Phase Extraction Limit of Detection Reproducibility of Results Osmolar Concentration Drinking Water Metal-Organic Frameworks Linear Models Lakes Neonicotinoids Hydrogen-Ion Concentration Water Pollutants, Chemical
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Determination of total plasma oxysterols by enzymatic hydrolysis, solid phase extraction and liquid chromatography coupled to mass-spectrometry.

Journal of pharmaceutical and biomedical analysis Dec 21, 2017
The potential use of cholesterol esterases was tested to avoid alkaline hydrolysis for cleavage of plasma esterified oxysterols. The enzymatic hydrolysis was optimized by testing two sources of enzyme-Pseudomonas and bovine pancreas, presence of surf...
Tandem Mass Spectrometry Pseudomonas aeruginosa Solid Phase Extraction Hydrolysis Animals Male Chromatography, Liquid Humans Bacterial Proteins Oxysterols Animals, Genetically Modified Reproducibility of Results Rats, Inbred F344 Calibration Steroid Hydroxylases Reference Standards Sterol Esterase Cytochrome P450 Family 7
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Design and validation of an automated solid phase extraction liquid chromatography coupled mass spectrometry method for the quantification of propofol in plasma.

Journal of pharmaceutical and biomedical analysis Dec 21, 2017
Propofol concentration in human plasma can be quantified by liquid chromatography coupled mass spectrometry. Sample preparation usually requires solid phase extraction to remove matrix components and enrich the analyte. To facilitate user-independent...
Humans Automation, Laboratory Reproducibility of Results Calibration Reference Standards Workflow Mass Spectrometry Anesthetics, Intravenous Propofol Solid Phase Extraction Chromatography, Liquid Linear Models Limit of Detection
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Development of a Competitive Time-Resolved Fluoroimmunoassay for Paclitaxel.

Phytochemical analysis : PCA Dec 20, 2017
INTRODUCTION: Paclitaxel (Tax) is a diterpene alkaloid isolated from Taxus species and has proved clinically effective in treating a number of malignancies. Current quantitative analytical methods for Tax such as high-performance liquid chromatograph...
Calibration Fluorescent Antibody Technique Taxus Time and Motion Studies Antibodies, Monoclonal Limit of Detection Rabbits Paclitaxel Humans Reproducibility of Results Immunoglobulin G Animals Enzyme-Linked Immunosorbent Assay Antineoplastic Agents, Phytogenic
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Simultaneous quantification of fluoxetine and norfluoxetine in colostrum and mature human milk using a 2-dimensional liquid chromatography-tandem mass spectrometry system.

Journal of pharmaceutical and biomedical analysis Dec 20, 2017
A two-dimensional liquid chromatography system coupled to triple quadrupole tandem mass spectrometer (2D LC-MS/MS) was employed for the determination of fluoxetine (FLU) and norfluoxetine (N-FLU) in colostrum and mature milk by direct sample injectio...
Linear Models Calibration Reference Standards Colostrum Fluoxetine Humans Chromatography, Liquid Female Limit of Detection Reproducibility of Results Workflow Milk, Human Tandem Mass Spectrometry
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Enhancing interpretability of automatically extracted machine learning features: application to a RBM-Random Forest system on brain lesion segmentation.

Medical image analysis Dec 20, 2017
Machine learning systems are achieving better performances at the cost of becoming increasingly complex. However, because of that, they become less interpretable, which may cause some distrust by the end-user of the system. This is especially importa...
Magnetic Resonance Imaging Stroke Image Interpretation, Computer-Assisted Humans Machine Learning Algorithms Reproducibility of Results Sensitivity and Specificity Brain Neoplasms
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Gold Nanoparticle-Based Paper Sensor for Simultaneous Detection of 11 Benzimidazoles by One Monoclonal Antibody.

Small (Weinheim an der Bergstrasse, Germany) Dec 20, 2017
A colloidal gold immunochromatographic assay based on a generic monoclonal antibody is developed for the simultaneous detection of benzimidazoles and metabolite residues in milk samples. The monoclonal antibody is prepared using 2-(methoxycarbonylami...
Reproducibility of Results Benzimidazoles Haptens Limit of Detection Animals Immunoassay Antibodies, Monoclonal Paper Gold Milk Metal Nanoparticles
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A biological network-based regularized artificial neural network model for robust phenotype prediction from gene expression data.

BMC bioinformatics Dec 19, 2017
BACKGROUND: Stratification of patient subpopulations that respond favorably to treatment or experience and adverse reaction is an essential step toward development of new personalized therapies and diagnostics. It is currently feasible to generate om...
Gene Regulatory Networks Models, Theoretical Support Vector Machine Gene Expression Regulation Humans Neural Networks, Computer Phenotype Reproducibility of Results
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