AIMC Topic: Retrospective Studies
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Predicting Immunotherapy Response in Unresectable Hepatocellular Carcinoma: A Comparative Study of Large Language Models and Human Experts.
Journal of medical systems
May 15, 2025
Hepatocellular carcinoma (HCC) is an aggressive cancer with limited biomarkers for predicting immunotherapy response. Recent advancements in large language models (LLMs) like GPT-4, GPT-4o, and Gemini offer the potential for enhancing clinical decisi...
Quantitative analysis and clinical determinants of orthodontically induced root resorption using automated tooth segmentation from CBCT imaging.
BMC oral health
May 8, 2025
BACKGROUND: Orthodontically induced root resorption (OIRR) is difficult to assess accurately using traditional 2D imaging due to distortion and low sensitivity. While CBCT offers more precise 3D evaluation, manual segmentation remains labor-intensive...
Enhancing clinical decision-making in closed pelvic fractures with machine learning models.
Biomolecules & biomedicine
May 8, 2025
Closed pelvic fractures can lead to severe complications, including hemodynamic instability (HI) and mortality. Accurate prediction of these risks is crucial for effective clinical management. This study aimed to utilize various machine learning (ML)...
Radiomic analysis based on machine learning of multi-sequences MR to assess early treatment response in locally advanced nasopharyngeal carcinoma.
Science progress
May 8, 2025
ObjectiveThe prediction of early response in locally advanced nasopharyngeal carcinoma (LA-NPC) after concurrent chemoradiotherapy (CCRT) is important for determining the need for timely consolidation therapy. We developed a radiomic analysis of mult...
A deep learning model combining circulating tumor cells and radiological features in the multi-classification of mediastinal lesions in comparison with thoracic surgeons: a large-scale retrospective study.
BMC medicine
May 7, 2025
BACKGROUND: CT images and circulating tumor cells (CTCs) are indispensable for diagnosing the mediastinal lesions by providing radiological and intra-tumoral information. This study aimed to develop and validate a deep multimodal fusion network (DMFN...
Explainable Machine Learning Models for Colorectal Cancer Prediction Using Clinical Laboratory Data.
Cancer control : journal of the Moffitt Cancer Center
May 7, 2025
IntroductionEarly diagnosis of colorectal cancer (CRC) poses a significant clinical challenge. This study aims to develop machine learning (ML) models for CRC risk prediction using clinical laboratory data.MethodsThis retrospective, single-center stu...
PET image nonuniformity texture features for metastasis risk prediction in osteosarcoma.
Nuclear medicine communications
May 6, 2025
OBJECTIVE: PET image analysis provides tumor heterogeneity data related to neoadjuvant chemotherapy response (NACR) and metastatic risk in osteosarcoma. Ki-67 expression is used to predict metastasis. The accuracy of prediction models with image quan...
Stacking classifiers based on integrated machine learning model: fusion of CT radiomics and clinical biomarkers to predict lymph node metastasis in locally advanced gastric cancer patients after neoadjuvant chemotherapy.
BMC cancer
May 6, 2025
BACKGROUND: The early prediction of lymph node positivity (LN+) after neoadjuvant chemotherapy (NAC) is crucial for optimizing individualized treatment strategies. This study aimed to integrate radiomic features and clinical biomarkers through machin...
Interpretable Prognostic Modeling for Postoperative Pancreatic Cancer Using Multi-machine Learning and Habitat Radiomics: A Multi-center Study.
Academic radiology
May 5, 2025
RATIONALE AND OBJECTIVES: Accurate risk stratification is critical for guiding personalized treatment in resectable pancreatic cancer (RPC). This retrospective study assessed the utility of habitat radiomics for predicting recurrence-free survival (R...
Prediction of EGFR Mutations in Lung Adenocarcinoma via CT Images: A Comparative Study of Intratumoral and Peritumoral Radiomics, Deep Learning, and Fusion Models.
Academic radiology
May 5, 2025
RATIONALE AND OBJECTIVES: This study aims to analyze the intratumoral and peritumoral characteristics of lung adenocarcinoma patients on the basis of chest CT images via radiomic and deep learning methods and to develop and validate a multimodel fusi...
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