The global resurgence of dengue presents an ongoing challenge for public health systems, particularly in low- and middle-income countries (LMICs) where conventional early warning systems (EWS) often suffer from reporting delays and under-detection. W...
Journal of chemical information and modeling
Aug 5, 2025
The use of artificial intelligence (AI) is increasingly integral to the drug-discovery process, and among AI-driven methodologies, deep generative models stand out as one of the most promising approaches for hit identification and optimization. Here,...
Current evidence for predictive models of post-stroke depression (PSD) risk based on machine learning (ML) remains limited. The aim of this study is to develop a superior predictive model based on ML algorithms for PSD in the Chinese population. We r...
BACKGROUND: Delirium frequently occurs as a severe complication among patients with acute pancreatitis (AP), contributing to extended hospital stays, higher mortality rates, and lasting cognitive deficits. The pathogenesis of delirium in this setting...
PURPOSE: To evaluate the performance of artificial intelligence (AI)-based coronary artery calcium scoring (CACS) on non-electrocardiogram (ECG)-gated chest CT, using manual quantification as the reference standard, while characterizing per-vessel re...
BACKGROUND: Acute cholangitis (AC) presents with significant clinical heterogeneity, and existing severity classifications have limited prognostic value in critically ill patients. Subtypes of AC in critically ill patients have not been investigated.
Cancer imaging : the official publication of the International Cancer Imaging Society
Aug 4, 2025
PURPOSE: Accurate preoperative grading of gliomas is critical for therapeutic planning and prognostic evaluation. We developed a noninvasive machine learning model leveraging whole-brain resting-state functional magnetic resonance imaging (rs-fMRI) b...
BACKGROUND AND OBJECTIVE: Adrenal incidentalomas (AIs) are predominantly adrenal adenomas (80%), with a smaller proportion (7%) being pheochromocytomas(PHEO). Adenomas are typically non-functional tumors managed through observation or medication, wit...
BACKGROUND: We aimed to develop an actionable and feasible prospective clinical model to estimate toxicity risk to assist chimeric antigen receptor (CAR) T-cell therapy providers with the management of patients with relapsed and/or refractory large B...
Chronic spontaneous urticaria is a common skin disorder with variable treatment responses. Second-generation H1-antihistamines are the first-line treatment for chronic spontaneous urticaria, yet many patients fail to respond to licensed doses. Predic...
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