AIMC Topic: ROC Curve

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Personalized medication recommendations for Parkinson's disease patients using gated recurrent units and SHAP interpretability.

Scientific reports May 30, 2025
Managing Parkinson's disease (PD) through medication can be challenging due to varying symptoms and disease duration. This study aims to demonstrate the potential of sequence-by-sequence algorithms in recommending personalized medication combinations...
Humans Algorithms Middle Aged ROC Curve Parkinson Disease Antiparkinson Agents Precision Medicine Female Aged Male
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A preliminary study of the reliability and validity of the Uyghur version of the NUCOG cognitive screening application.

BMC neurology May 29, 2025
INTRODUCTION: Technological advances and artificial intelligence now make it feasible to administer cognitive assessments on touch-screen devices. The aim of this study is to develop a Uyghur version of the NUCOG cognitive screening application and e...
ROC Curve Neuropsychological Tests China Cognitive Dysfunction Dementia Aged Aged, 80 and over Humans Male Female Middle Aged Reproducibility of Results
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Deep learning for predicting invasive recurrence of ductal carcinoma in situ: leveraging histopathology images and clinical features.

EBioMedicine May 28, 2025
BACKGROUND: Ductal Carcinoma In Situ (DCIS) can progress to ipsilateral invasive breast cancer (IBC) but over 75% of DCIS lesions do not progress if untreated. Currently, DCIS that might progress to IBC cannot reliably be identified. Therefore, most ...
Humans Prognosis Female Aged ROC Curve Carcinoma, Intraductal, Noninfiltrating Neoplasm Recurrence, Local Proportional Hazards Models Adult Breast Neoplasms Middle Aged Deep Learning
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Characteristic genes and immune landscape of interstitial cystitis.

PloS one May 28, 2025
BACKGROUND: Interstitial cystitis (IC) was still a disease with the exclusive diagnosis and lacked an effective gold standard. It was of great significance to find diagnostic markers for IC. Our study was aimed to screen characteristic genes via mach...
Cystitis, Interstitial Gene Expression Profiling ROC Curve Adaptor Proteins, Signal Transducing Urinary Bladder Humans Machine Learning Algorithms
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Automatic identification of Parkinsonism using clinical multi-contrast brain MRI: a large self-supervised vision foundation model strategy.

EBioMedicine May 27, 2025
BACKGROUND: Valid non-invasive biomarkers for Parkinson's disease (PD) and Parkinson-plus syndrome (PPS) are urgently needed. Based on our recent self-supervised vision foundation model the Shift Window UNET TRansformer (Swin UNETR), which uses clini...
Magnetic Resonance Imaging Parkinson Disease Parkinsonian Disorders Male Humans Middle Aged Neural Networks, Computer ROC Curve Image Processing, Computer-Assisted Brain Female Aged
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Immunogenic cell death biomarkers for sepsis diagnosis and mechanism via integrated bioinformatics.

Scientific reports May 27, 2025
Immunogenic cell death (ICD) has been implicated in sepsis, a condition with high mortality, through mechanisms involving endoplasmic reticulum stress and other pathophysiological pathways. This study aimed to identify and validate ICD-related biomar...
Humans Biomarkers Gene Expression Profiling Sepsis ROC Curve Cell Death Gene Regulatory Networks Computational Biology Databases, Genetic
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Rapid diagnosis of TERT promoter mutation using Terahertz absorption spectroscopy in glioblastoma.

Scientific reports May 27, 2025
Glioblastoma (GBM) is a highly aggressive brain tumor with poor outcomes and limited treatment options. The telomerase reverse transcriptase (TERT) promoter mutation, one of the key biomarkers in GBM, is linked to tumor progression and prognosis. Thi...
Brain Neoplasms Telomerase Male Terahertz Spectroscopy Humans Middle Aged Female ROC Curve Biomarkers, Tumor Principal Component Analysis Glioblastoma Mutation Promoter Regions, Genetic
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Dual-energy CT combined with histogram parameters in the assessment of perineural invasion in colorectal cancer.

International journal of colorectal disease May 27, 2025
PURPOSE: The purpose is to evaluate the predictive value of dual-energy CT (DECT) combined with histogram parameters and a clinical prediction model for perineural invasion (PNI) in colorectal cancer (CRC).
Neoplasm Invasiveness Multivariate Analysis Peripheral Nerves Adult Colorectal Neoplasms Male Middle Aged ROC Curve Logistic Models Support Vector Machine Retrospective Studies Tomography, X-Ray Computed Female Aged Humans
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Development and validation of a hypoxemia prediction model in middle-aged and elderly outpatients undergoing painless gastroscopy.

Scientific reports May 23, 2025
Hypoxemia is a common complication associated with anesthesia in painless gastroscopy. With the aging of the social population, the number of cases of hypoxemia among middle-aged and elderly patients is increasing. However, tools for predicting hypox...
Male Gastroscopy Middle Aged Female Logistic Models Humans ROC Curve Risk Factors Support Vector Machine Machine Learning Aged Hypoxia Retrospective Studies Aged, 80 and over Outpatients
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Development and validation of a multi-omics hemorrhagic transformation model based on hyperattenuated imaging markers following mechanical thrombectomy.

Scientific reports May 23, 2025
This study aimed to develop a predictive model integrating clinical, radiomics, and deep learning (DL) features of hyperattenuated imaging markers (HIM) from computed tomography scans immediately following mechanical thrombectomy (MT) to predict hemo...
Tomography, X-Ray Computed Female Aged Male Hemorrhage Middle Aged Humans Thrombectomy Deep Learning Prospective Studies ROC Curve Multiomics
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