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Sepsis

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Predicting patients with septic shock and sepsis through analyzing whole-blood expression of NK cell-related hub genes using an advanced machine learning framework.

Frontiers in immunology
BACKGROUND: Sepsis is a life-threatening condition that causes millions of deaths globally each year. The need for biomarkers to predict the progression of sepsis to septic shock remains critical, with rapid, reliable methods still lacking. Transcrip...

[Construction of a back propagation neural network model for predicting urosepsis after flexible ureteroscopic lithotripsy].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences
OBJECTIVES: To analyze the association of serum heparin-binding protein (HBP) and C-reactive protein (CRP) levels with urosepsis following flexible ureteroscopic lithotripsy (FURL) and to construct a back propagation neural network prediction model.

Explainable machine learning for early prediction of sepsis in traumatic brain injury: A discovery and validation study.

PloS one
BACKGROUND: People with traumatic brain injury (TBI) are at high risk for infection and sepsis. The aim of the study was to develop and validate an explainable machine learning(ML) model based on clinical features for early prediction of the risk of ...

Prediction of mortality in sepsis patients using stacked ensemble machine learning algorithm.

Journal of postgraduate medicine
INTRODUCTION: Machine learning (ML) has been tried in predicting outcomes following sepsis. This study aims to identify the utility of stacked ensemble algorithm in predicting mortality.

A novel classical machine learning framework for early sepsis prediction using electronic health record data from ICU patients.

Computers in biology and medicine
Sepsis, a life-threatening condition triggered by the body's response to infection, remains a significant global health challenge, annually affecting millions in the United States alone with substantial mortality and healthcare costs. Early predictio...

Utilizing integrated bioinformatics and machine learning approaches to elucidate biomarkers linking sepsis to fatty acid metabolism-associated genes.

Scientific reports
Sepsis, characterized as a systemic inflammatory response triggered by the invasion of pathogens, represents a continuum that may escalate from mild systemic infection to severe sepsis, potentially resulting in septic shock and multiple organ dysfunc...

Machine learning-based model for predicting the occurrence and mortality of nonpulmonary sepsis-associated ARDS.

Scientific reports
OBJECTIVE: The objective was to establish a machine learning-based model for predicting the occurrence and mortality of nonpulmonary sepsis-associated ARDS.

Brain imaging and machine learning reveal uncoupled functional network for contextual threat memory in long sepsis.

Scientific reports
Positron emission tomography (PET) utilizes radiotracers like [F]fluorodeoxyglucose (FDG) to measure brain activity in health and disease. Performing behavioral tasks between the FDG injection and the PET scan allows the FDG signal to reflect task-re...

Utilizing deep learning-based causal inference to explore vancomycin's impact on continuous kidney replacement therapy necessity in blood culture-positive intensive care unit patients.

Microbiology spectrum
Patients with positive blood cultures in the intensive care unit (ICU) are at high risk for septic acute kidney injury requiring continuous kidney replacement therapy (CKRT), especially when treated with vancomycin. This study developed a machine lea...

A Universal Method for Fingerprinting Multiplexed Bacteria: Evolving Pruned Sensor Arrays via Machine Learning-Driven Combinatorial Group-Specificity Strategy.

ACS nano
Array-based sensing technology holds immense potential for discerning the intricacies of biological systems. Nevertheless, developing a universal strategy for simultaneous identification of diverse types of multianalytes and meeting the diagnostic ne...