AIMC Topic: Severity of Illness Index
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Automated grading of rectocele with an MRI radiomics model.
Scientific reports
Jul 2, 2025
To develop an automated grading model for rectocele (RC) based on radiomics and evaluate its efficacy. This study retrospectively analyzed a total of 9,392 magnetic resonance imaging (MRI) images obtained from 222 patients who underwent dynamic magne...
Epicardial adipose tissue, myocardial remodelling and adverse outcomes in asymptomatic aortic stenosis: a post hoc analysis of a randomised controlled trial.
Heart (British Cardiac Society)
Jun 26, 2025
BACKGROUND: Epicardial adipose tissue represents a metabolically active visceral fat depot that is in direct contact with the left ventricular myocardium. While it is associated with coronary artery disease, little is known regarding its role in aort...
Evaluating real-world performance of an automated offline glaucoma AI on a smartphone fundus camera across glaucoma severity stages.
PloS one
Jun 26, 2025
PURPOSE: Leveraging an artificial intelligence system (AI) for glaucoma screening can mitigate the current challenges and provide prompt detection and management crucial in averting irreversible blindness. The study reports the real-world performance...
Computed tomography-derived quantitative imaging biomarkers enable the prediction of disease manifestations and survival in patients with systemic sclerosis.
RMD open
Jun 25, 2025
INTRODUCTION: Systemic sclerosis (SSc) is a complex inflammatory vasculopathy with diverse symptoms and variable disease progression. Despite its known impact on body composition (BC), clinical decision-making has yet to incorporate these biomarkers....
Sleep disturbances and PTSD: identifying baseline predictors of insomnia response in an intensive treatment programme.
European journal of psychotraumatology
Jun 23, 2025
This study examined whether baseline demographic and clinical variables could predict clinically significant reductions in insomnia symptoms among veterans receiving a 2-week Cognitive Processing Therapy (CPT)-based intensive PTSD treatment programm...
Inflammation-related 5-hydroxymethylation signatures as markers for clinical presentations of coronary artery disease.
Cardiovascular diabetology
Jun 23, 2025
BACKGROUND: Coronary angiography remains the gold standard for diagnosing coronary artery disease (CAD), but its invasive nature limits its applicability for widespread screening. Identifying non-invasive molecular markers could improve CAD classific...
Inflammation Mediators
5-Methylcytosine
Non-ST Elevated Myocardial Infarction
Predictive Value of Tests
ST Elevation Myocardial Infarction
Coronary Artery Disease
Reproducibility of Results
Aged
Humans
Male
Machine Learning
Middle Aged
Biomarkers
Risk Assessment
Severity of Illness Index
Prognosis
Epigenesis, Genetic
Female
Inflammation
DNA Methylation
Cell-Free Nucleic Acids
Gut microbiota alterations are linked to COVID-19 severity in North African and European populations.
NPJ biofilms and microbiomes
Jun 13, 2025
Although COVID-19 primarily affects the respiratory system, many patients experience gastrointestinal symptoms, suggesting a role for the gut microbiota in disease pathogenesis. To explore this, we performed shotgun metagenomic sequencing on stool sa...
Real-world effectiveness of cariprazine in major depressive disorder and bipolar I disorder in the United States.
Journal of medical economics
Jun 10, 2025
AIMS: The efficacy of cariprazine for major depressive disorder (MDD) (adjunctive therapy) and bipolar I (BP-I) depression has been demonstrated in clinical trials. This study evaluated the real-world effectiveness of cariprazine in reducing depressi...
Mortality Prediction Performance Under Geographical, Temporal, and COVID-19 Pandemic Dataset Shift: External Validation of the Global Open-Source Severity of Illness Score Model.
Critical care explorations
Jun 4, 2025
BACKGROUND: Risk-prediction models are widely used for quality of care evaluations, resource management, and patient stratification in research. While established models have long been used for risk prediction, healthcare has evolved significantly, a...
Artificial intelligence-based Raynaud's quantification index (ARTIX): an objective mobile-based tool for patient-centered assessment of Raynaud's phenomenon.
Arthritis research & therapy
Jun 3, 2025
BACKGROUND: We aimed to develop an artificial intelligence algorithm able to assess Raynaud's phenomenon (RP) from mobile phone photography, ensuring as a patient-centered, image-based method for RP quantification.
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