AIMC Topic: Singapore
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Role of Brain Age Gap as a Mediator in the Relationship Between Cognitive Impairment Risk Factors and Cognition.
Neurology
Jun 18, 2025
BACKGROUND AND OBJECTIVES: Cerebrovascular disease (CeVD) and cognitive impairment risk factors contribute to cognitive decline, but the role of brain age gap (BAG) in mediating this relationship remains unclear, especially in Southeast Asian populat...
Rate of brain aging associates with future executive function in Asian children and older adults.
eLife
Jun 16, 2025
Brain age has emerged as a powerful tool to understand neuroanatomical aging and its link to health outcomes like cognition. However, there remains a lack of studies investigating the rate of brain aging and its relationship to cognition. Furthermore...
Preterm birth trends and risk factors in a multi-ethnic Asian population: A retrospective study from 2017 to 2023, can we screen and predict this?
Annals of the Academy of Medicine, Singapore
May 21, 2025
INTRODUCTION: Preterm birth (PTB) remains a leading cause of perinatal morbidity and mortality worldwide. Understanding Singapore's PTB trends and associated risk factors can inform effective strategies for screening and intervention. This study anal...
Predictive Analysis of Amyotrophic Lateral Sclerosis Progression and Mortality in a Clinic Cohort From Singapore.
Muscle & nerve
Apr 23, 2025
INTRODUCTION: There is currently no comprehensive Amyotrophic Lateral Sclerosis (ALS) patient database in Singapore comparable to those available in Europe and the United States. We established the Singapore ALS registry (SingALS) to draw meaningful ...
Machine learning to risk stratify chest pain patients with non-diagnostic electrocardiogram in an Asian emergency department.
Annals of the Academy of Medicine, Singapore
Apr 22, 2025
INTRODUCTION: Elevated troponin, while essential for diagnosing myocardial infarction, can also be present in non-myocardial infarction conditions. The myocardial-ischaemic-injury-index (MI3) algorithm is a machine learning algorithm that considers a...
Can off-the-shelf visual large language models detect and diagnose ocular diseases from retinal photographs?
BMJ open ophthalmology
Apr 7, 2025
BACKGROUND: The advent of generative artificial intelligence has led to the emergence of multiple vision large language models (VLLMs). This study aimed to evaluate the capabilities of commonly available VLLMs, such as OpenAI's GPT-4V and Google's Ge...
Deep learning-based normative database of anterior chamber dimensions for angle closure assessment: the Singapore Chinese Eye Study.
The British journal of ophthalmology
Mar 20, 2025
BACKGROUND/ AIMS: The lack of context for anterior segment optical coherence tomography (ASOCT) measurements impedes its clinical utility. We established the normative distribution of anterior chamber depth (ACD), area (ACA) and width (ACW) and lens ...
Effectiveness of Transformer-Based Large Language Models in Identifying Adverse Drug Reaction Relations from Unstructured Discharge Summaries in Singapore.
Drug safety
Feb 21, 2025
INTRODUCTION: Transformer-based large language models (LLMs) have transformed the field of natural language processing and led to significant advancements in various text processing tasks. However, the applicability of these LLMs in identifying relat...
Early detection of disease outbreaks and non-outbreaks using incidence data: A framework using feature-based time series classification and machine learning.
PLoS computational biology
Feb 13, 2025
Forecasting the occurrence and absence of novel disease outbreaks is essential for disease management, yet existing methods are often context-specific, require a long preparation time, and non-outbreak prediction remains understudied. To address this...
Using ChatGPT for medical education: the technical perspective.
BMC medical education
Feb 7, 2025
BACKGROUND: The chatbot application Bennie and the Chats was introduced due to the outbreak of COVID-19, which is aimed to provide substitution for teaching conventional clinical history-taking skills. It was implemented with DialogFlow with preset r...
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