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Somatosensory Cortex

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Decoding Movements from Cortical Ensemble Activity Using a Long Short-Term Memory Recurrent Network.

Neural computation
Although many real-time neural decoding algorithms have been proposed for brain-machine interface (BMI) applications over the years, an optimal, consensual approach remains elusive. Recent advances in deep learning algorithms provide new opportunitie...

Machine Learning: Advanced Image Segmentation Using ilastik.

Methods in molecular biology (Clifton, N.J.)
Segmentation is one of the most ubiquitous problems in biological image analysis. Here we present a machine learning-based solution to it as implemented in the open source ilastik toolkit. We give a broad description of the underlying theory and demo...

Abnormal Low-Frequency Oscillations Reflect Trait-Like Pain Ratings in Chronic Pain Patients Revealed through a Machine Learning Approach.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Measures of moment-to-moment fluctuations in brain activity of an individual at rest have been shown to be a sensitive and reliable metric for studying pathological brain mechanisms across various chronic pain patient populations. However, the relati...

Shared spatiotemporal category representations in biological and artificial deep neural networks.

PLoS computational biology
Visual scene category representations emerge very rapidly, yet the computational transformations that enable such invariant categorizations remain elusive. Deep convolutional neural networks (CNNs) perform visual categorization at near human-level ac...

Structured networks support sparse traveling waves in rodent somatosensory cortex.

Proceedings of the National Academy of Sciences of the United States of America
Neurons responding to different whiskers are spatially intermixed in the superficial layer 2/3 (L2/3) of the rodent barrel cortex, where a single whisker deflection activates a sparse, distributed neuronal population that spans multiple cortical colu...

Modeling spike-wave discharges by a complex network of neuronal oscillators.

Neural networks : the official journal of the International Neural Network Society
PURPOSE: The organization of neural networks and the mechanisms, which generate the highly stereotypical for absence epilepsy spike-wave discharges (SWDs) is heavily debated. Here we describe such a model which can both reproduce the characteristics ...

Quantification of task-dependent cortical activation evoked by robotic continuous wrist joint manipulation in chronic hemiparetic stroke.

Journal of neuroengineering and rehabilitation
BACKGROUND: Cortical damage after stroke can drastically impair sensory and motor function of the upper limb, affecting the execution of activities of daily living and quality of life. Motor impairment after stroke has been thoroughly studied, howeve...

Revealing unobserved factors underlying cortical activity with a rectified latent variable model applied to neural population recordings.

Journal of neurophysiology
The activity of sensory cortical neurons is not only driven by external stimuli but also shaped by other sources of input to the cortex. Unlike external stimuli, these other sources of input are challenging to experimentally control, or even observe,...

Using goal-driven deep learning models to understand sensory cortex.

Nature neuroscience
Fueled by innovation in the computer vision and artificial intelligence communities, recent developments in computational neuroscience have used goal-driven hierarchical convolutional neural networks (HCNNs) to make strides in modeling neural single-...

Electrical and Optical Activation of Mesoscale Neural Circuits with Implications for Coding.

The Journal of neuroscience : the official journal of the Society for Neuroscience
UNLABELLED: Artificial activation of neural circuitry through electrical microstimulation and optogenetic techniques is important for both scientific discovery of circuit function and for engineered approaches to alleviate various disorders of the ne...