AIMC Topic: Somatosensory Cortex

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Modeling spike-wave discharges by a complex network of neuronal oscillators.

Neural networks : the official journal of the International Neural Network Society
PURPOSE: The organization of neural networks and the mechanisms, which generate the highly stereotypical for absence epilepsy spike-wave discharges (SWDs) is heavily debated. Here we describe such a model which can both reproduce the characteristics ...

Quantification of task-dependent cortical activation evoked by robotic continuous wrist joint manipulation in chronic hemiparetic stroke.

Journal of neuroengineering and rehabilitation
BACKGROUND: Cortical damage after stroke can drastically impair sensory and motor function of the upper limb, affecting the execution of activities of daily living and quality of life. Motor impairment after stroke has been thoroughly studied, howeve...

Revealing unobserved factors underlying cortical activity with a rectified latent variable model applied to neural population recordings.

Journal of neurophysiology
The activity of sensory cortical neurons is not only driven by external stimuli but also shaped by other sources of input to the cortex. Unlike external stimuli, these other sources of input are challenging to experimentally control, or even observe,...

Machine Learning-Based Clustering of Layer-Resolved fMRI Activation and Functional Connectivity Within the Primary Somatosensory Cortex in Nonhuman Primates.

Human brain mapping
Delineating the functional organization of mesoscale cortical columnar structure is essential for understanding brain function. We have previously demonstrated a high spatial correspondence between BOLD fMRI and LFP responses to tactile stimuli in th...

Artificial touch feedback using microstimulation of human somatosensory cortex to convey grip force from a robotic hand.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Invasive brain-machine interfaces can help restore function through the control of external devices while the addition of intracortical microstimulation (ICMS) can elicit sensations of touch and help provide further benefits for individuals living wi...

A neural surveyor to map touch on the body.

Proceedings of the National Academy of Sciences of the United States of America
Perhaps the most recognizable sensory map in all of neuroscience is the somatosensory homunculus. Although it seems straightforward, this simple representation belies the complex link between an activation in a somatotopic map and the associated touc...

A brain-computer interface that evokes tactile sensations improves robotic arm control.

Science (New York, N.Y.)
Prosthetic arms controlled by a brain-computer interface can enable people with tetraplegia to perform functional movements. However, vision provides limited feedback because information about grasping objects is best relayed through tactile feedback...

Machine Learning: Advanced Image Segmentation Using ilastik.

Methods in molecular biology (Clifton, N.J.)
Segmentation is one of the most ubiquitous problems in biological image analysis. Here we present a machine learning-based solution to it as implemented in the open source ilastik toolkit. We give a broad description of the underlying theory and demo...

Using goal-driven deep learning models to understand sensory cortex.

Nature neuroscience
Fueled by innovation in the computer vision and artificial intelligence communities, recent developments in computational neuroscience have used goal-driven hierarchical convolutional neural networks (HCNNs) to make strides in modeling neural single-...

Electrical and Optical Activation of Mesoscale Neural Circuits with Implications for Coding.

The Journal of neuroscience : the official journal of the Society for Neuroscience
UNLABELLED: Artificial activation of neural circuitry through electrical microstimulation and optogenetic techniques is important for both scientific discovery of circuit function and for engineered approaches to alleviate various disorders of the ne...