IEEE journal of biomedical and health informatics
Jan 17, 2022
The combination of Raman spectroscopy and deep learning technology provides an automatic, rapid, and accurate scheme for the clinical diagnosis of pathogenic bacteria. However, the accuracy of existing deep learning methods is still limited because o...
Accurate and rapid identification of infectious bacteria is important in medicine. Raman microspectroscopy holds great promise in performing label-free identification at the single-cell level. However, due to the naturally weak Raman signal, it is a ...
Synchronously detecting multiple Raman spectral signatures in two-dimensional/three-dimensional (2D/3D) hyperspectral Raman analysis is a daunting challenge. The underlying reasons notwithstanding the enormous volume of the data and also the complexi...
Recently, Raman Spectroscopy (RS) was demonstrated to be a non-destructive way of cancer diagnosis, due to the uniqueness of RS measurements in revealing molecular biochemical changes between cancerous vs. normal tissues and cells. In order to design...
Surface-Enhanced Raman Spectroscopy (SERS)-based biomolecule detection has been a challenge due to large variations in signal intensity, spectral profile, and nonlinearity. Recent advances in machine learning offer great opportunities to address thes...
Klebsiella pneumoniae has become the number one bacterial pathogen that causes high mortality in clinical settings worldwide. Clinical K. pneumoniae strains with carbapenem resistance and/or hypervirulent phenotypes cause higher mortality comparing w...
Raman spectroscopy enables nondestructive, label-free imaging with unprecedented molecular contrast, but is limited by slow data acquisition, largely preventing high-throughput imaging applications. Here, we present a comprehensive framework for high...
Analytical methods : advancing methods and applications
Nov 18, 2021
Crohn's disease (CD) is an idiopathic chronic inflammatory bowel disease without a cure. Most of the CD patients are firstly diagnosed by invasive endoscopy, and clinical and pathological examinations are further required to confirm the diagnosis. He...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Nov 13, 2021
Electron portable Raman spectroscopy tools for ore mineral identification are widely used in raw ore analysis and mineral process engineering. This paper demonstrates an extremely fast and accurate method for identifying unknown ore mineral samples b...
Raman spectroscopy is increasingly being used in biology, forensics, diagnostics, pharmaceutics and food science applications. This growth is triggered not only by improvements in the computational and experimental setups but also by the development ...