AIMC Topic: Transcriptome

Clear Filters Showing 561 to 570 of 856 articles

StressGenePred: a twin prediction model architecture for classifying the stress types of samples and discovering stress-related genes in arabidopsis.

BMC genomics Dec 20, 2019
BACKGROUND: Recently, a number of studies have been conducted to investigate how plants respond to stress at the cellular molecular level by measuring gene expression profiles over time. As a result, a set of time-series gene expression data for the ...
Gene Expression Profiling Transcriptome Genetic Association Studies Computational Biology Neural Networks, Computer Machine Learning Phenotype Arabidopsis Models, Biological Stress, Physiological Genes, Plant
View on PubMed DOI

Transcriptome analysis and identification of genes associated with chicken sperm storage duration.

Poultry science Dec 13, 2019
The sperm storage tubules located in the mucosal folds of the uterovaginal junction (UVJ) are the primary site of sperm storage in chicken hens after natural mating or artificial insemination (AI). The short-term sperm storage (24 h after mating or A...
Insemination, Artificial Animals Transcriptome Male Chickens Gene Expression Profiling Spermatozoa Avian Proteins
View on PubMed DOI

Discovery and annotation of novel microRNAs in the porcine genome by using a semi-supervised transductive learning approach.

Genomics Dec 6, 2019
Despite the broad variety of available microRNA (miRNA) prediction tools, their application to the discovery and annotation of novel miRNA genes in domestic species is still limited. In this study we designed a comprehensive pipeline (eMIRNA) for miR...
Sequence Homology, Nucleic Acid Sus scrofa RNA Precursors Transcriptome Nucleotide Motifs Machine Learning MicroRNAs RNA-Seq Genome Muscle, Skeletal Algorithms Genomics Genetic Loci Animals Liver Molecular Sequence Annotation
View on PubMed DOI

Global transcriptome analysis reveals relevant effects at environmental concentrations of cypermethrin in honey bees (Apis mellifera).

Environmental pollution (Barking, Essex : 1987) Dec 4, 2019
Cypermethrin is a frequently used insecticide in agriculture and households but its chronic and molecular effects are poorly known are . Here we describe effects of sublethal cypermethrin exposure on the global transcriptome in the brain of honey bee...
Bees Animals Gene Expression Profiling Environmental Pollutants Transcriptome Genetic Markers Reverse Transcriptase Polymerase Chain Reaction Insecticides RNA-Seq Pyrethrins RNA, Messenger Sequence Analysis, RNA
View on PubMed DOI

CDSeq: A novel complete deconvolution method for dissecting heterogeneous samples using gene expression data.

PLoS computational biology Dec 2, 2019
Quantifying cell-type proportions and their corresponding gene expression profiles in tissue samples would enhance understanding of the contributions of individual cell types to the physiological states of the tissue. Current approaches that address ...
Humans Computer Simulation Gene Expression Profiling Unsupervised Machine Learning Leukocytes Pattern Recognition, Automated Databases, Nucleic Acid Transcriptome Computational Biology Sequence Analysis, RNA Cell Line
View on PubMed DOI

Approach for the Definition of radiomiRNomic Signatures for Breast Cancer Differential Diagnosis.

International journal of molecular sciences Nov 20, 2019
UNLABELLED: Personalized medicine relies on the integration and consideration of specific characteristics of the patient, such as tumor phenotypic and genotypic profiling.
Magnetic Resonance Imaging MicroRNAs Breast Neoplasms Humans Machine Learning Biomarkers, Tumor Female Transcriptome Gene Regulatory Networks
View on PubMed DOI

Four transcription profile-based models identify novel prognostic signatures in oesophageal cancer.

Journal of cellular and molecular medicine Nov 19, 2019
Oesophageal cancer (ESCA) is a clinically challenging disease with poor prognosis and health-related quality of life. Here, we investigated the transcriptome of ESCA to identify high risk-related signatures. A total of 159 ESCA patients of The Cancer...
Esophageal Neoplasms Esophageal Squamous Cell Carcinoma Tumor Cells, Cultured Transcriptome Gene Expression Regulation, Neoplastic Cell Proliferation Apoptosis Biomarkers, Tumor Male Middle Aged Humans Machine Learning Algorithms Prognosis Female Survival Rate
View on PubMed DOI

DeePathology: Deep Multi-Task Learning for Inferring Molecular Pathology from Cancer Transcriptome.

Scientific reports Nov 11, 2019
Despite great advances, molecular cancer pathology is often limited to the use of a small number of biomarkers rather than the whole transcriptome, partly due to computational challenges. Here, we introduce a novel architecture of Deep Neural Network...
Gene Expression Regulation, Neoplastic Data Mining Disease Susceptibility Organ Specificity Gene Expression Profiling Transcriptome Deep Learning Computational Biology Pathology, Molecular Humans Neural Networks, Computer Algorithms Reproducibility of Results Neoplasms
View on PubMed DOI

Molecular expression profiles of morphologically defined hippocampal neuron types: Empirical evidence and relational inferences.

Hippocampus Oct 9, 2019
Gene and protein expressions are key determinants of cellular function. Neurons are the building blocks of brain circuits, yet the relationship between their molecular identity and the spatial distribution of their dendritic inputs and axonal outputs...
Humans Transcriptome Neurons Knowledge Bases Data Mining Hippocampus Empirical Research
View on PubMed DOI

Identification of a blood-based 12-gene signature that predicts the severity of coronary artery stenosis: An integrative approach based on gene network construction, Support Vector Machine algorithm, and multi-cohort validation.

Atherosclerosis Oct 9, 2019
BACKGROUND AND AIMS: We aimed to identify a blood-based gene expression score (GES) to predict the severity of coronary artery stenosis in patients with known or suspected coronary artery disease (CAD) by integrative use of gene network construction,...
Predictive Value of Tests Coronary Stenosis Gene Regulatory Networks Genetic Predisposition to Disease Humans Nomograms Gene Expression Profiling Decision Support Techniques Aged Support Vector Machine Transcriptome Phenotype Male China Retrospective Studies Middle Aged Female Severity of Illness Index Reproducibility of Results Risk Factors
View on PubMed DOI
Popular Topics
Recent Journals