AIMC Topic: Treatment Failure

Clear Filters Showing 21 to 30 of 34 articles

Salvage HDR Brachytherapy: Multiple Hypothesis Testing Versus Machine Learning Analysis.

International journal of radiation oncology, biology, physics Mar 13, 2018
PURPOSE: Salvage high-dose-rate brachytherapy (sHDRB) is a treatment option for recurrences after prior radiation therapy. However, only approximately 50% of patients benefit, with the majority of second recurrences after salvage brachytherapy occurr...
Recurrence Humans Linear Models Salvage Therapy Brachytherapy Treatment Failure Machine Learning Retrospective Studies Male Prostatic Neoplasms
View on PubMed DOI

Efficacy and safety of lebrikizumab in adult patients with mild-to-moderate asthma not receiving inhaled corticosteroids.

Respiratory medicine Dec 13, 2017
BACKGROUND: Asthma is a heterogeneous and complex disease in both its clinical course and response to treatment. IL-13 is central to Type 2 inflammation and contributes to many features of asthma. In a previous Phase 2 study, lebrikizumab, an anti-IL...
Treatment Failure Quinolines Administration, Inhalation Injections, Subcutaneous Anti-Asthmatic Agents Male Humans Middle Aged Double-Blind Method Female Glucocorticoids Forced Expiratory Volume Adult Severity of Illness Index Acetates Asthma Sulfides Treatment Outcome Cyclopropanes Antibodies, Monoclonal
View on PubMed DOI

First Report of NRG Oncology/Radiation Therapy Oncology Group 0622: A Phase 2 Trial of Samarium-153 Followed by Salvage Prostatic Fossa Irradiation in High-Risk Clinically Nonmetastatic Prostate Cancer After Radical Prostatectomy.

International journal of radiation oncology, biology, physics Nov 21, 2017
PURPOSE: To investigate the utility of Sm lexidronam (Quadramet) in the setting of men with prostate cancer status post radical prostatectomy who develop biochemical failure with no clinical evidence of osseous metastases.
Humans Aged Aged, 80 and over Male Middle Aged Organophosphorus Compounds Prostatic Neoplasms Treatment Failure Salvage Therapy Prostate-Specific Antigen Organometallic Compounds Neoplasm Grading Prostatectomy
View on PubMed DOI

Radiomic machine-learning classifiers for prognostic biomarkers of advanced nasopharyngeal carcinoma.

Cancer letters Jun 10, 2017
We aimed to identify optimal machine-learning methods for radiomics-based prediction of local failure and distant failure in advanced nasopharyngeal carcinoma (NPC). We enrolled 110 patients with advanced NPC. A total of 970 radiomic features were ex...
Humans Decision Support Techniques ROC Curve Area Under Curve Support Vector Machine Magnetic Resonance Imaging Carcinoma Predictive Value of Tests High-Throughput Screening Assays Reproducibility of Results Image Interpretation, Computer-Assisted Risk Factors Nasopharyngeal Carcinoma Linear Models Nasopharyngeal Neoplasms Treatment Failure Risk Assessment Diagnosis, Computer-Assisted
View on PubMed DOI

Comparative risk of failure of ABC/3TC or TDF/FTC based first-line regimens in patients with a high viral load.

HIV medicine Aug 26, 2015
OBJECTIVES: To compare the efficacy, in current clinical practice, of first regimens containing abacavir with lamivudine (ABC/3TC) or tenofovir with emtricitabine (TDF/FTC) in patients with baseline viral load ≥100,000 HIV-1 RNA copies/mL.
Tenofovir Emtricitabine Drug Therapy, Combination France Dideoxynucleosides Propensity Score Treatment Failure Risk Assessment HIV Infections Viral Load Lamivudine Humans Prospective Studies Female Male
View on PubMed DOI

Risk factors for recurrent implantation failure as defined by the European Society for Human Reproduction and Embryology.

Human reproduction (Oxford, England) Jun 1, 2025
STUDY QUESTION: What are the unrecognized risk factors for recurrent implantation failure (RIF) as defined in the ESHRE recommendation?
Humans Infertility, Female Pregnancy Embryo Implantation Female Risk Factors Adult Embryo Transfer Anti-Mullerian Hormone Treatment Failure Reproductive Techniques, Assisted
View on PubMed DOI

Noninvasive prediction of failure of the conservative treatment in lateral epicondylitis by clinicoradiological features and elbow MRI radiomics based on interpretable machine learning: a multicenter cohort study.

Journal of orthopaedic surgery and research May 24, 2025
OBJECTIVES: To develop and validate an interpretable machine learning model based on clinicoradiological features and radiomic features based on magnetic resonance imaging (MRI) to predict the failure of conservative treatment in lateral epicondyliti...
Conservative Treatment Tennis Elbow Humans Cohort Studies Machine Learning Magnetic Resonance Imaging Radiomics Retrospective Studies Predictive Value of Tests Male Female Middle Aged Aged Adult Treatment Failure
View on PubMed DOI

Machine Learning Model Predictors of Intrapleural Tissue Plasminogen Activator and DNase Failure in Pleural Infection: A Multicenter Study.

Annals of the American Thoracic Society Feb 1, 2025
Intrapleural enzyme therapy (IET) with tissue plasminogen activator (tPA) and DNase has been shown to reduce the need for surgical intervention for complicated parapneumonic effusion/empyema (CPPE/empyema). Failure of IET may lead to delayed care an...
Female Risk Factors Aged Male Middle Aged Humans Machine Learning Retrospective Studies Tissue Plasminogen Activator Deoxyribonucleases Treatment Failure Empyema, Pleural Logistic Models United States Fibrinolytic Agents Pleural Effusion
View on PubMed DOI

Image-Based Deep Neural Network for Individualizing Radiotherapy Dose Is Transportable Across Health Systems.

JCO clinical cancer informatics Jan 1, 2023
PURPOSE: We developed a deep neural network that queries the lung computed tomography-derived feature space to identify radiation sensitivity parameters that can predict treatment failures and hence guide the individualization of radiotherapy dose. I...
Neural Networks, Computer Tomography, X-Ray Computed Proportional Hazards Models Radiotherapy Dosage Humans Treatment Failure
View on PubMed DOI

Feasibility of salvage robotic partial nephrectomy after ablative treatment failure (UroCCR-62 study).

Minerva urology and nephrology Apr 1, 2022
BACKGROUND: Ablative therapies (AT) are increasingly being offered to patients with kidney tumors. In cases of failure or local relapse, salvage surgery may be required. Such procedures often require an open approach, are difficult and have received ...
Neoplasm Recurrence, Local Treatment Failure Nephrectomy Humans Retrospective Studies Aged Middle Aged Robotics Robotic Surgical Procedures Feasibility Studies
View on PubMed DOI
Popular Topics
Recent Journals