AIMC Topic: Treatment Failure

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First Report of NRG Oncology/Radiation Therapy Oncology Group 0622: A Phase 2 Trial of Samarium-153 Followed by Salvage Prostatic Fossa Irradiation in High-Risk Clinically Nonmetastatic Prostate Cancer After Radical Prostatectomy.

International journal of radiation oncology, biology, physics Nov 21, 2017
PURPOSE: To investigate the utility of Sm lexidronam (Quadramet) in the setting of men with prostate cancer status post radical prostatectomy who develop biochemical failure with no clinical evidence of osseous metastases.
Organophosphorus Compounds Salvage Therapy Treatment Failure Humans Organometallic Compounds Prostatectomy Middle Aged Aged Prostatic Neoplasms Aged, 80 and over Prostate-Specific Antigen Male Neoplasm Grading
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Radiomic machine-learning classifiers for prognostic biomarkers of advanced nasopharyngeal carcinoma.

Cancer letters Jun 10, 2017
We aimed to identify optimal machine-learning methods for radiomics-based prediction of local failure and distant failure in advanced nasopharyngeal carcinoma (NPC). We enrolled 110 patients with advanced NPC. A total of 970 radiomic features were ex...
Linear Models Treatment Failure Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms Diagnosis, Computer-Assisted Decision Support Techniques Reproducibility of Results ROC Curve Risk Factors Support Vector Machine Risk Assessment Magnetic Resonance Imaging Carcinoma Predictive Value of Tests Humans High-Throughput Screening Assays Area Under Curve Image Interpretation, Computer-Assisted
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Comparative risk of failure of ABC/3TC or TDF/FTC based first-line regimens in patients with a high viral load.

HIV medicine Aug 26, 2015
OBJECTIVES: To compare the efficacy, in current clinical practice, of first regimens containing abacavir with lamivudine (ABC/3TC) or tenofovir with emtricitabine (TDF/FTC) in patients with baseline viral load ≥100,000 HIV-1 RNA copies/mL.
Tenofovir Emtricitabine Drug Therapy, Combination Prospective Studies Risk Assessment France Humans Propensity Score Female HIV Infections Male Treatment Failure Viral Load Dideoxynucleosides Lamivudine
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Risk factors for recurrent implantation failure as defined by the European Society for Human Reproduction and Embryology.

Human reproduction (Oxford, England) Jun 1, 2025
STUDY QUESTION: What are the unrecognized risk factors for recurrent implantation failure (RIF) as defined in the ESHRE recommendation?
Humans Pregnancy Infertility, Female Embryo Implantation Anti-Mullerian Hormone Treatment Failure Female Reproductive Techniques, Assisted Risk Factors Adult Embryo Transfer
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Noninvasive prediction of failure of the conservative treatment in lateral epicondylitis by clinicoradiological features and elbow MRI radiomics based on interpretable machine learning: a multicenter cohort study.

Journal of orthopaedic surgery and research May 24, 2025
OBJECTIVES: To develop and validate an interpretable machine learning model based on clinicoradiological features and radiomic features based on magnetic resonance imaging (MRI) to predict the failure of conservative treatment in lateral epicondyliti...
Conservative Treatment Tennis Elbow Humans Cohort Studies Machine Learning Magnetic Resonance Imaging Retrospective Studies Predictive Value of Tests Female Treatment Failure Radiomics Aged Male Adult Middle Aged
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Machine Learning Model Predictors of Intrapleural Tissue Plasminogen Activator and DNase Failure in Pleural Infection: A Multicenter Study.

Annals of the American Thoracic Society Feb 1, 2025
Intrapleural enzyme therapy (IET) with tissue plasminogen activator (tPA) and DNase has been shown to reduce the need for surgical intervention for complicated parapneumonic effusion/empyema (CPPE/empyema). Failure of IET may lead to delayed care an...
Female Risk Factors Aged Male Middle Aged Humans Machine Learning Retrospective Studies Tissue Plasminogen Activator Logistic Models Deoxyribonucleases United States Treatment Failure Fibrinolytic Agents Empyema, Pleural Pleural Effusion
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Image-Based Deep Neural Network for Individualizing Radiotherapy Dose Is Transportable Across Health Systems.

JCO clinical cancer informatics Jan 1, 2023
PURPOSE: We developed a deep neural network that queries the lung computed tomography-derived feature space to identify radiation sensitivity parameters that can predict treatment failures and hence guide the individualization of radiotherapy dose. I...
Neural Networks, Computer Tomography, X-Ray Computed Proportional Hazards Models Radiotherapy Dosage Humans Treatment Failure
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Feasibility of salvage robotic partial nephrectomy after ablative treatment failure (UroCCR-62 study).

Minerva urology and nephrology Apr 1, 2022
BACKGROUND: Ablative therapies (AT) are increasingly being offered to patients with kidney tumors. In cases of failure or local relapse, salvage surgery may be required. Such procedures often require an open approach, are difficult and have received ...
Neoplasm Recurrence, Local Treatment Failure Nephrectomy Humans Retrospective Studies Robotics Robotic Surgical Procedures Feasibility Studies Aged Middle Aged
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Prediction of treatment failure of tuberculosis using support vector machine with genetic algorithm.

International journal of mycobacteriology Jan 1, 2021
BACKGROUND: Tuberculosis (TB) is a disease that mainly affects human lungs. It can be fatal if the treatment is delayed. This study investigates the prediction of treatment failure of TB patients focusing on the features which contributes mostly for ...
Treatment Failure Myanmar Humans Forecasting Support Vector Machine Tuberculosis
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Machine-Learning Algorithms Predict Graft Failure After Liver Transplantation.

Transplantation Apr 1, 2017
BACKGROUND: The ability to predict graft failure or primary nonfunction at liver transplant decision time assists utilization of scarce resource of donor livers, while ensuring that patients who are urgently requiring a liver transplant are prioritiz...
Adolescent Time Factors ROC Curve Tissue Donors Area Under Curve Liver Transplantation Patient Selection Graft Survival Predictive Value of Tests Adult Male Middle Aged Machine Learning Risk Assessment Algorithms Treatment Failure Reproducibility of Results Decision Support Techniques Humans Donor Selection Risk Factors Databases, Factual Victoria Aged Female Young Adult
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