AIMC Topic: Treatment Outcome

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Deep learning-based clustering for endotyping and post-arthroplasty response classification using knee osteoarthritis multiomic data.

Annals of the rheumatic diseases Feb 12, 2025
OBJECTIVES: Primary knee osteoarthritis (KOA) is a heterogeneous disease with clinical and molecular contributors. Biofluids contain microRNAs and metabolites that can be measured by omic technologies. Multimodal deep learning is adept at uncovering ...
Middle Aged Deep Learning Treatment Outcome Cluster Analysis Humans Female Synovial Fluid Metabolomics Aged MicroRNAs Male Arthroplasty, Replacement, Knee Osteoarthritis, Knee
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Efficacy and effectiveness of therapist-guided internet versus face-to-face cognitive behavioural therapy for depression via counterfactual inference using naturalistic registers and machine learning in Finland: a retrospective cohort study.

The lancet. Psychiatry Feb 12, 2025
BACKGROUND: According to meta-analyses of randomised controlled trials (RCTs), therapist-guided internet-delivered cognitive behavioural therapy (iCBT) is as effective a treatment for depression as traditional face-to-face CBT (fCBT), despite its sub...
Female Depression Humans Finland Machine Learning Adult Treatment Outcome Cognitive Behavioral Therapy Retrospective Studies Male Registries Depressive Disorder Middle Aged Internet
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Comparative analysis of machine learning models for predicting pathological complete response to neoadjuvant chemotherapy in breast cancer: An MRI radiomics approach.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) Feb 12, 2025
PURPOSE: The aim of this work is to compare different machine learning models for predicting pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) in breast cancer using radiomics features from dynamic contrast-enhanced magnetic reso...
Neoadjuvant Therapy Humans Magnetic Resonance Imaging Machine Learning Female Radiomics Middle Aged Aged Image Processing, Computer-Assisted Adult Treatment Outcome Breast Neoplasms
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An interpretable machine learning model assists in predicting induction chemotherapy response and survival for locoregionally advanced nasopharyngeal carcinoma using MRI: a multicenter study.

European radiology Feb 10, 2025
OBJECTIVES: To develop and validate an interpretable and generalized machine learning model using MRI for the individualized prediction of induction chemotherapy (ICT) response and survival in locoregionally advanced nasopharyngeal carcinoma (LANPC).
Prognosis Retrospective Studies Female Aged Humans Neural Networks, Computer Machine Learning Magnetic Resonance Imaging Nasopharyngeal Carcinoma Nasopharyngeal Neoplasms Induction Chemotherapy Adult Male Middle Aged Treatment Outcome
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New Perspectives and State of the Art in Interventional Radiotherapy (Brachytherapy) for Head and Neck Tumors.

Magyar onkologia Feb 10, 2025
AIM: This review aims to evaluate the role of interventional radiotherapy (IRT - brachytherapy) in the clinical management of head and neck (H&N) cancers, focusing on recent technological advancements and their impact on clinical outcomes.
Radiotherapy, Image-Guided Artificial Intelligence Quality of Life Treatment Outcome Head and Neck Neoplasms Humans Radiotherapy Planning, Computer-Assisted Brachytherapy Radiotherapy Dosage Radiotherapy, Intensity-Modulated
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Novel pre-spatial data fusion deep learning approach for multimodal volumetric outcome prediction models in radiotherapy.

Medical physics Feb 10, 2025
BACKGROUND: Given the recent increased emphasis on multimodal neural networks to solve complex modeling tasks, the problem of outcome prediction for a course of treatment can be framed as fundamentally multimodal in nature. A patient's response to tr...
Treatment Outcome Head and Neck Neoplasms Radiotherapy Planning, Computer-Assisted Humans Deep Learning
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Biopsychosocial based machine learning models predict patient improvement after total knee arthroplasty.

Scientific reports Feb 10, 2025
Total knee arthroplasty (TKA) is an effective treatment for end stage osteoarthritis. However, biopsychosocial features are not routinely considered in TKA clinical decision-making, despite increasing evidence to support their role in patient recover...
Humans Machine Learning Female Aged Male Middle Aged Arthroplasty, Replacement, Knee Quality of Life Osteoarthritis, Knee Treatment Outcome Bayes Theorem
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Comparing Phenotypes for Acute and Long-Term Response to Atrial Fibrillation Ablation Using Machine Learning.

Circulation. Arrhythmia and electrophysiology Feb 10, 2025
BACKGROUND: It is difficult to identify patients with atrial fibrillation (AF) most likely to respond to ablation. While any arrhythmia patient may recur after acutely successful ablation, AF is unusual in that patients may have long-term arrhythmia ...
Registries Atrial Fibrillation Heart Rate Catheter Ablation Electrophysiologic Techniques, Cardiac Electrocardiography Treatment Outcome Action Potentials Predictive Value of Tests Male Middle Aged Time Factors Humans Machine Learning Phenotype Female Aged
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Can muscle synergies shed light on the mechanisms underlying motor gains in response to robot-assisted gait training in children with cerebral palsy?

Journal of neuroengineering and rehabilitation Feb 7, 2025
BACKGROUND: Children with cerebral palsy (CP) often experience gait impairments. Robot-assisted gait training (RGT) has been shown to have beneficial effects in this patient population. However, clinical outcomes of RGT vary substantially from patien...
Muscle, Skeletal Robotics Electromyography Gait Adolescent Child Treatment Outcome Exercise Therapy Cerebral Palsy Gait Disorders, Neurologic Humans Female Male
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Genome data based deep learning identified new genes predicting pharmacological treatment response of attention deficit hyperactivity disorder.

Translational psychiatry Feb 7, 2025
Although the efficacy of pharmacy in the treatment of attention deficit/hyperactivity disorder (ADHD) has been well established, the lack of predictors of treatment response poses great challenges for personalized treatment. The current study employe...
Female Male Deep Learning Adolescent Humans Membrane Proteins Treatment Outcome Genome-Wide Association Study Attention Deficit Disorder with Hyperactivity Child Polymorphism, Single Nucleotide
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