PURPOSE: The use of soluble cocrystals is a promising strategy for delivering poorly soluble drugs. However, precipitation of poorly soluble crystal form during dissolution hinders the successful tablet development of cocrystals. This work was aimed ...
Axi-symmetric numerical simulations are carried out to study the dynamics of a plug introduced through a mixed-stream injection in supercritical fluid chromatographic columns. The computational fluid dynamics model developed in this work takes into a...
The present study was undertaken to improve rosuvastatin (RSV) bioavailability and pharmacological response through formation of SNES using Perilla frutescens oil as lipid carrier. The composition of oil was estimated by fatty acid methyl ester (FAME...
While insect grooming has been observed and documented for over one hundred years, we present the first quantitative analysis of this highly dynamic process. Pollinating insects, like honey bees, purposely cover themselves with millions of pollen par...
UNLABELLED: Some patients with dysphagia are prone to aspiration of low-viscosity liquids. Thickened liquids are often used in attempts to prevent aspiration. The patients should be given thickened liquids with suitable thickness, and the thickness s...
In this paper a novel flexible joint is proposed for robotic fish pectoral fins, which enables a swimming behavior emulating the fin motions of many aquatic animals. In particular, the pectoral fin operates primarily in the rowing mode, while undergo...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Jan 27, 2016
In recent years, intelligent prosthetic knees have been developed that enable amputees to walk as normally as possible when compared to healthy subjects. Although semi-active prosthetic knees utilizing magnetorheological (MR) dampers offer several ad...
Pharmaceutical development and technology
Dec 20, 2015
CONTEXT: Nanostructured lipid carrier (NLC) dispersions present low viscosity and poor mucoadhesive properties, which reduce the pre-corneal residence time and consequently, the bioavailability of ocular drugs.
A polysaccharide fraction (FMPS) was isolated from floral mushrooms cultivated in Huangshan Mountain, and the rheological properties of FMPS in aqueous solutions were investigated. The FMPS solution showed shear-thinning behavior at 25°C. Dynamic vis...
International journal of pharmaceutics
Nov 10, 2015
Melt granulation in fluid bed processors is an emerging technique, but literature data regarding the modeling of this granulation method are lacking. In the present study different techniques (response surface analysis, multilayer perceptron neural n...
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