White matter hyperintensities (WMH) are neuroimaging markers linked to an elevated risk of cognitive decline. WMH severity is typically assessed via visual rating scales and through volumetric segmentation. While visual rating scales are commonly use...
The progression of Alzheimer's disease (AD) involves complex changes in brain structure and function that are driven by their interaction, making structure-function coupling (SFC) a valuable indicator for early detection of AD. Static SFC refers to t...
Tractography parcellation classifies streamlines reconstructed from diffusion MRI into anatomically defined fiber tracts for clinical and research applications. However, clinical scans often have incomplete fields of view (FOV) where brain regions ar...
Given the relationship between hippocampal atrophy and cognitive impairment in various pathological conditions, hippocampus segmentation from MRI is an important task in neuroimaging. Manual segmentation, though considered the gold standard, is time-...
The shape of the brain's white matter connections is relatively unexplored in diffusion magnetic resonance imaging (dMRI) tractography analysis. While it is known that tract shape varies in populations and across the human lifespan, it is unknown if ...
Compared to nonverbal cognition such as executive or memory functions, language-related cognition generally appears to remain more stable until later in life. Nevertheless, different language-related processes, for example, verbal fluency versus voca...
Delineating the functional organization of mesoscale cortical columnar structure is essential for understanding brain function. We have previously demonstrated a high spatial correspondence between BOLD fMRI and LFP responses to tactile stimuli in th...
Autism is a neurodevelopmental condition affecting ~1% of the population. Recently, machine learning models have been trained to classify participants with autism using their neuroimaging features, though the performance of these models varies in the...
While the use of naturalistic stimuli such as movie clips for understanding individual differences and brain-behaviour relationships attracts increasing interest, the influence of stimulus selection remains largely unclear. By using machine learning ...
Disorders of the central nervous system, including neurodegenerative diseases, frequently affect the brainstem and can present with focal atrophy. This study aimed to (1) optimize deep learning-based brainstem segmentation for a wide range of patholo...