International journal of radiation oncology, biology, physics
May 9, 2025
PURPOSE: The XXXXX trial is a multi-institutional phase I/II study utilizing a combined PSMA PET/MRI approach to treat dominant intraprostatic lesions (DILs) and affected lymph nodes in unfavorable intermediate and high-risk prostate cancer using a f...
International journal of radiation oncology, biology, physics
May 5, 2025
Dramatic strides have been made in real-time adaptive radiation therapy, where treating single tumors as dynamic but rigid bodies has demonstrated a halving of toxicities for prostate cancer. However, the human body is much more complex than a rigid ...
International journal of radiation oncology, biology, physics
Apr 1, 2025
PURPOSE: Cone beam computed tomography-based online adaptive radiation therapy (ART) allows significantly smaller planning target volume margins for patients treated with adaptive stereotactic partial breast irradiation. However, this approach places...
International journal of radiation oncology, biology, physics
Jan 25, 2025
PURPOSE: This study evaluates the feasibility of using robotic-assisted bronchoscopy with cone beam computed tomography (RB-CBCT) platform to perform low-dose-rate brachytherapy (LDR-BT) implants in a mechanically ventilated human cadaveric model. Po...
International journal of radiation oncology, biology, physics
Jan 25, 2025
PURPOSE: Investigators and funding organizations desire knowledge on topics and trends in publicly funded research but current efforts for manual categorization have been limited in breadth and depth of understanding. We present a semiautomated analy...
International journal of radiation oncology, biology, physics
Jan 22, 2025
This white paper examines the potential of pioneering technologies and artificial intelligence-driven solutions in advancing clinical trials involving radiation therapy. As the field of radiation therapy evolves, the integration of cutting-edge appro...
International journal of radiation oncology, biology, physics
Jan 11, 2025
PURPOSE: High dose rate (HDR) prostate brachytherapy (BT) procedure requires image-guided needle insertion. Given that general anesthesia is often employed during the procedure, minimizing overall planning time is crucial. In this study, we explore t...
International journal of radiation oncology, biology, physics
Jan 7, 2025
PURPOSE: Deep learning is a promising approach to increase reproducibility and time-efficiency of gross tumor volume (GTV) delineation in head and neck cancer, but model evaluation primarily relies on manual GTV delineations as reference annotation, ...
International journal of radiation oncology, biology, physics
Nov 16, 2024
PURPOSE: To develop a deep learning method exploiting active learning and source-free domain adaptation for gross tumor volume delineation in nasopharyngeal carcinoma (NPC), addressing the variability and inaccuracy when deploying segmentation models...
International journal of radiation oncology, biology, physics
Oct 1, 2024
PURPOSE: Magnetic resonance (MR)-guided radiation therapy enables online adaptation to address intra- and interfractional changes. To address the need of high-fidelity synthetic computed tomography (synCT) required for dose calculation, we developed ...