AIMC Topic: Adult

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Does bariatric surgery really prevent deterioration of renal function?

Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery
BACKGROUND: Obesity is related to impaired renal function; bariatric surgery is associated with an improvement in renal function.

Non-weight-based enoxaparin dosing subtherapeutic in trauma patients.

The Journal of surgical research
BACKGROUND: We report our experience dosing and monitoring enoxaparin with anti-factor Xa activity (anti-FXaA) levels for venous thromboembolism prophylaxis in trauma patients (TP).

Fuzzy approximate entropy analysis of resting state fMRI signal complexity across the adult life span.

Medical engineering & physics
In this study, we present a method for measuring functional magnetic resonance imaging (fMRI) signal complexity using fuzzy approximate entropy (fApEn) and compare it with the established sample entropy (SampEn). Here we use resting state fMRI datase...

Bioequivalence of fixed-dose combinations of dapagliflozin and metformin with single-component tablets in healthy subjects and the effect of food on bioavailability.

Clinical pharmacology in drug development
The pharmacokinetics (PK) of dapagliflozin and metformin administered as fixed-dose combination (FDC) tablets (2.5 mg dapagliflozin/850 mg metformin or 5 mg dapagliflozin/1000 mg metformin) or as separate tablets in healthy subjects were evaluated in...

Human-Robot Interaction: Does Robotic Guidance Force Affect Gait-Related Brain Dynamics during Robot-Assisted Treadmill Walking?

PloS one
In order to determine optimal training parameters for robot-assisted treadmill walking, it is essential to understand how a robotic device interacts with its wearer, and thus, how parameter settings of the device affect locomotor control. The aim of ...

Validation of a six degree-of-freedom robotic system for hip in vitro biomechanical testing.

Journal of biomechanics
Currently, there exists a need for a more thorough understanding of native hip joint kinematics to improve the understanding of pathological conditions, injury mechanisms, and surgical interventions. A biomechanical testing system able to accomplish ...

Small, dense high-density lipoprotein 3 particles exhibit defective antioxidative and anti-inflammatory function in familial hypercholesterolemia: Partial correction by low-density lipoprotein apheresis.

Journal of clinical lipidology
BACKGROUND: Familial hypercholesterolemia (FH) features elevated oxidative stress and accelerated atherosclerosis driven by elevated levels of atherogenic lipoproteins relative to subnormal levels of atheroprotective high-density lipoprotein (HDL). S...

Pain Intensity Recognition Rates via Biopotential Feature Patterns with Support Vector Machines.

PloS one
BACKGROUND: The clinically used methods of pain diagnosis do not allow for objective and robust measurement, and physicians must rely on the patient's report on the pain sensation. Verbal scales, visual analog scales (VAS) or numeric rating scales (N...

Estimation of ground reaction forces and ankle moment with multiple, low-cost sensors.

Journal of neuroengineering and rehabilitation
BACKGROUND: Wearable sensor systems can provide data for at-home gait analyses and input to controllers for rehabilitation devices but they often have reduced estimation accuracy compared to laboratory systems. The goal of this study is to evaluate a...

Prediction of delayed graft function after kidney transplantation: comparison between logistic regression and machine learning methods.

BMC medical informatics and decision making
BACKGROUND: Predictive models for delayed graft function (DGF) after kidney transplantation are usually developed using logistic regression. We want to evaluate the value of machine learning methods in the prediction of DGF.