AIMC Topic: Adult
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An oral robotic pill reliably and safely delivers teriparatide with high bioavailability in healthy volunteers: A phase 1 study.
British journal of clinical pharmacology
Apr 7, 2025
AIMS: The incidence of osteoporosis is projected to exceed 70 million people over the age of 65 years by 2030. Osteoanabolic agents, such as teriparatide and abaloparatide, are not only effective in reducing fracture incidence but also improve skelet...
A neural network approach to glomerular filtration rate estimation: a single-centre retrospective audit.
Nuclear medicine communications
Apr 7, 2025
OBJECTIVES: The 2009 Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation without race correction factor is frequently used for an estimate of glomerular filtration rate (eGFR) and to support a single-sample GFR regime. This study exa...
AI-Driven Detection and Measurement of Keratinized Gingiva in Dental Photographs: Validation Using Reference Retainers.
Journal of clinical periodontology
Apr 7, 2025
AIM: To evaluate a deep learning (DL) model for detecting keratinized gingiva (KG) in dental photographs and validate its clinical applicability using reference retainers for calibration.
Prediction of new-onset migraine using clinical-genotypic data from the HUNT Study: a machine learning analysis.
The journal of headache and pain
Apr 7, 2025
BACKGROUND: Migraine is associated with a range of symptoms and comorbid disorders and has a strong genetic basis, but the currently identified risk loci only explain a small portion of the heritability, often termed the "missing heritability". We ai...
Evaluation of Large Language Models in Tailoring Educational Content for Cancer Survivors and Their Caregivers: Quality Analysis.
JMIR cancer
Apr 7, 2025
BACKGROUND: Cancer survivors and their caregivers, particularly those from disadvantaged backgrounds with limited health literacy or racial and ethnic minorities facing language barriers, are at a disproportionately higher risk of experiencing sympto...
Is artificial intelligence superior to traditional regression methods in predicting prognosis of adult traumatic brain injury?
Neurosurgical review
Apr 7, 2025
Traumatic brain injury (TBI) is a significant global health issue with high morbidity and mortality rates. Recent studies have shown that machine learning algorithms outperform traditional logistic regression models in predicting functional outcomes ...
Prediction of Seronegative Hashimoto's thyroiditis using machine learning models based on ultrasound radiomics: a multicenter study.
BMC immunology
Apr 7, 2025
BACKGROUND: Seronegative Hashimoto's thyroiditis is often underdiagnosed due to the lack of antibody markers. Combining ultrasound radiomics with machine learning offers potential for early detection in patients with normal thyroid function.
DP-MP: a novel cross-subject fatigue detection framework with DANN-based prototypical representation and mix-up pairwise learning.
Journal of neural engineering
Apr 7, 2025
. Electroencephalography (EEG) is widely recognized as an effective method for detecting fatigue. However, practical applications of EEG for fatigue detection in real-world scenarios are often challenging, particularly in cases involving subjects not...
Structural brain pattern abnormalities in tinnitus with and without hearing loss.
Hearing research
Apr 6, 2025
OBJECTIVE: Subjective tinnitus often coexists with hearing loss, and they share common pathophysiological mechanisms. This comorbidity induces whole-brain gray matter volume (GMV) alterations, manifesting as distributed structural changes in neural n...
Common genetic variants do not impact clinical prediction of methotrexate treatment outcomes in early rheumatoid arthritis.
Journal of internal medicine
Apr 6, 2025
BACKGROUND: Methotrexate (MTX) is the mainstay initial treatment of rheumatoid arthritis (RA), but individual response varies and remains difficult to predict. The role of genetics remains unclear, but studies suggest its importance.
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