AIMC Topic: Aged, 80 and over
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Natural language processing assisted detection of inappropriate proton pump inhibitor use in adult hospitalised patients.
European journal of hospital pharmacy : science and practice
Aug 21, 2025
OBJECTIVES: To establish a clinical application monitoring system for proton pump inhibitors (PPI-MS) and to enhance the detection and intervention of inappropriate PPI use in adult hospitalised patients.
Advancing fall risk prediction in older adults with cognitive frailty: A machine learning approach using 2-year clinical data.
PloS one
Aug 21, 2025
Falls are a critical concern in older adults with cognitive frailty (CF). However, previous studies have not fully examined whether machine learning models can predict falls in older individuals with CF. The 2-year longitudinal data set from the Kore...
A smart secure virtual reality immersive application for alzheimer's and dementia patients.
Scientific reports
Aug 20, 2025
Alzheimer's disease (AD) poses significant challenges for the elderly, leading to cognitive decline, social isolation, and lower quality of life. Current interventions often require cumbersome wearable devices e.g. the camera-based monitoring that ma...
Unsupervised clustering of biochemical markers reveals health profiles associated with function and survival in active aging.
Scientific reports
Aug 20, 2025
This study explores the relationships between biochemical phenotypes identified using machine learning, and key health outcomes, including body composition, physical function, and mortality risk. Data were collected from 536 physically active Spanish...
Optimizing timing and cost-effective use of plasma biomarkers in Alzheimer's disease.
Alzheimer's research & therapy
Aug 20, 2025
BACKGROUND AND OBJECTIVES: Early and cost-effective identification of amyloid positivity is crucial for Alzheimer's disease (AD) diagnosis. While amyloid PET is the gold standard, plasma biomarkers such as phosphorylated tau 217 (pTau217) provide a p...
Effect of discontinuing antipsychotic medications on the risk of hospitalization in long-term care: a machine learning-based analysis.
BMC medicine
Aug 20, 2025
BACKGROUND: Antipsychotic medications are frequently prescribed to older residents of long-term care facilities (LTCFs) despite their limited efficacy and considerable safety risks. While discontinuation of these drugs might help reduce their associa...
Factors that influence technophobia in Chinese older patients with ischemic stroke: a cross-sectional survey.
BMC geriatrics
Aug 19, 2025
BACKGROUND: Older patients with ischemic stroke often have a large number of medical needs, technophobia refers to the irrational anxiety and fear of digital technologies such as mobile communication equipment, artificial intelligence and robots, res...
Multimodal anti fraud education improves cognitive emotional and behavioral engagement in older adults.
Scientific reports
Aug 11, 2025
This study examines the differential effectiveness of video-based versus text-based anti-fraud educational interventions in improving cognitive comprehension, emotional engagement, and behavioral intentions among older adults. Using a stratified samp...
AI-driven fusion of multimodal data for Alzheimer's disease biomarker assessment.
Nature communications
Aug 11, 2025
Alzheimer's disease (AD) diagnosis hinges on detecting amyloid beta (Aβ) plaques and neurofibrillary tau (τ) tangles, typically assessed using PET imaging. While accurate, these modalities are expensive and not widely accessible, limiting their utili...
Machine learning based analysis of leucocyte cell population data by Sysmex XN series hematology analyzer for the diagnosis of bacteremia.
Scientific reports
Aug 8, 2025
In clinical practice, early recognition of bacteremia leads to prognostic improvement. Recently, cell population data (CPD) from the Sysmex XN-series hematology analyzer has attracted attention as a new method for the early diagnosis of bacteremia, b...
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