AIMC Topic: Aged, 80 and over
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The impact of Alzheimer's disease on cortical complexity and its underlying biological mechanisms.
Brain research bulletin
Apr 4, 2025
BACKGROUND: Alzheimer's disease (AD) might impact the complexity of cerebral cortex, and the underlying biological mechanisms responsible for cortical changes in the AD cortex remain unclear.
Leveraging Artificial Intelligence to Uncover Symptom Burden in Palliative Care: Analysis of Nonscheduled Visits Using a Phi-3 Small Language Model.
JCO global oncology
Apr 4, 2025
PURPOSE: This study aimed to differentiate nonscheduled visits (NSVs) in an outpatient palliative care setting that are driven by or accompanied by uncontrolled symptoms from those that are administrative or routine, such as prescription refills and ...
DEMENTIA: A Hybrid Attention-Based Multimodal and Multi-Task Learning Framework With Expert Knowledge for Alzheimer's Disease Assessment From Speech.
IEEE journal of biomedical and health informatics
Apr 4, 2025
The prevalence of Alzheimer's disease (AD) is rising annually, imposing a severe burden on patients and society. Therefore, assisted AD assessment is crucial. The decline in language function and the cognitive impairment it reflects are key external ...
Prediction of PD-L1 expression in NSCLC patients using PET/CT radiomics and prognostic modelling for immunotherapy in PD-L1-positive NSCLC patients.
Clinical radiology
Apr 2, 2025
AIM: To develop a positron emission tomography/computed tomography (PET/CT)-based radiomics model for predicting programmed cell death ligand 1 (PD-L1) expression in non-small cell lung cancer (NSCLC) patients and estimating progression-free survival...
Development of Multiparametric Prognostic Models for Stereotactic Magnetic Resonance Guided Radiation Therapy of Pancreatic Cancers.
International journal of radiation oncology, biology, physics
Apr 2, 2025
PURPOSE: Stereotactic magnetic resonance guided adaptive radiation therapy (SMART) is a new option for local treatment of unresectable pancreatic ductal adenocarcinoma, showing interesting survival and local control (LC) results. Despite this, some p...
Machine Learning Models for Frailty Classification of Older Adults in Northern Thailand: Model Development and Validation Study.
JMIR aging
Apr 2, 2025
BACKGROUND: Frailty is defined as a clinical state of increased vulnerability due to the age-associated decline of an individual's physical function resulting in increased morbidity and mortality when exposed to acute stressors. Early identification ...
Data-Driven Prognostication in Distal Medium Vessel Occlusions Using Explainable Machine Learning.
AJNR. American journal of neuroradiology
Apr 2, 2025
BACKGROUND AND PURPOSE: Distal medium vessel occlusions (DMVOs) are estimated to cause acute ischemic stroke in 25%-40% of cases. Prognostic models can inform patient counseling and research by enabling outcome predictions. However, models designed s...
Understanding patterns of loneliness in older long-term care users using natural language processing with free text case notes.
PloS one
Apr 2, 2025
Loneliness and social isolation are distressing for individuals and predictors of mortality, yet data on their impact on publicly funded long-term care is limited. Using recent advances in natural language processing (NLP), we analysed pseudonymised ...
Identifying progression subphenotypes of Alzheimer's disease from large-scale electronic health records with machine learning.
Journal of biomedical informatics
Apr 1, 2025
OBJECTIVE: Identification of clinically meaningful subphenotypes of disease progression can enhance the understanding of disease heterogeneity and underlying pathophysiology. In this study, we propose a machine learning framework to identify subpheno...
Perspectives on AI and Novel Technologies Among Older Adults, Clinicians, Payers, Investors, and Developers.
JAMA network open
Apr 1, 2025
IMPORTANCE: Artificial intelligence (AI) and novel technologies, such as remote sensors, robotics, and decision support algorithms, offer the potential for improving the health and well-being of older adults, but the priorities of key partners across...
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