AIMC Topic: Aged, 80 and over

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Applying Machine Learning Algorithms to Segment High-Cost Patient Populations.

Journal of general internal medicine
BACKGROUND: Efforts to improve the value of care for high-cost patients may benefit from care management strategies targeted at clinically distinct subgroups of patients.

Correlation of the modified Medical Research Council dyspnea scale with airway structure assessed by three-dimensional CT in patients with chronic obstructive pulmonary disease.

Respiratory medicine
BACKGROUND: Dyspnea is a common symptom in chronic obstructive pulmonary disease (COPD). The modified Medical Research Council (mMRC) dyspnea scale is a widely used questionnaire to assess dyspnea. However, the relationship of the mMRC dyspnea scale ...

Chronic Kidney Disease stratification using office visit records: Handling data imbalance via hierarchical meta-classification.

BMC medical informatics and decision making
BACKGROUND: Chronic Kidney Disease (CKD) is one of several conditions that affect a growing percentage of the US population; the disease is accompanied by multiple co-morbidities, and is hard to diagnose in-and-of itself. In its advanced forms it car...

Wrist accelerometer shape feature derivation methods for assessing activities of daily living.

BMC medical informatics and decision making
BACKGROUND: There has been an increasing interest in understanding the usefulness of wrist-based accelerometer data for physical activity (PA) assessment due to the ease of use and higher user compliance than other body placements. PA assessment stud...

Automated Abdominal Segmentation of CT Scans for Body Composition Analysis Using Deep Learning.

Radiology
Purpose To develop and evaluate a fully automated algorithm for segmenting the abdomen from CT to quantify body composition. Materials and Methods For this retrospective study, a convolutional neural network based on the U-Net architecture was traine...

Probiotic and selenium co-supplementation, and the effects on clinical, metabolic and genetic status in Alzheimer's disease: A randomized, double-blind, controlled trial.

Clinical nutrition (Edinburgh, Scotland)
BACKGROUND AND AIMS: Combined probiotic and selenium supplementation may improve Alzheimer's disease (AD) by correcting metabolic abnormalities, and attenuating inflammation and oxidative stress. This study aimed to determine the effects of probiotic...

A minimal set of physiomarkers in continuous high frequency data streams predict adult sepsis onset earlier.

International journal of medical informatics
PURPOSE: Sepsis is a life-threatening condition with high mortality rates and expensive treatment costs. To improve short- and long-term outcomes, it is critical to detect at-risk sepsis patients at an early stage.

Validation of Prediction Models for Critical Care Outcomes Using Natural Language Processing of Electronic Health Record Data.

JAMA network open
IMPORTANCE: Accurate prediction of outcomes among patients in intensive care units (ICUs) is important for clinical research and monitoring care quality. Most existing prediction models do not take full advantage of the electronic health record, usin...

Association Between Early Intravenous Fluids Provided by Paramedics and Subsequent In-Hospital Mortality Among Patients With Sepsis.

JAMA network open
IMPORTANCE: Early administration of intravenous fluids is recommended for all patients with sepsis, but the association of this treatment with mortality may depend on the patient's initial blood pressure.