AIMC Topic: Aged, 80 and over

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Generalizability of AI-based image segmentation and centering estimation algorithm: a multi-region, multi-center, and multi-scanner study.

Radiation protection dosimetry
We created and validated an open-access AI algorithm (AIc) for assessing image segmentation and patient centering in a multi-body-region, multi-center, and multi-scanner study. Our study included 825 head, chest, and abdomen-pelvis CT from 275 patien...

WMH-DualTasker: A Weakly Supervised Deep Learning Model for Automated White Matter Hyperintensities Segmentation and Visual Rating Prediction.

Human brain mapping
White matter hyperintensities (WMH) are neuroimaging markers linked to an elevated risk of cognitive decline. WMH severity is typically assessed via visual rating scales and through volumetric segmentation. While visual rating scales are commonly use...

Examination of the relationship between D-amino acid profiles and cognitive function in individuals with mild cognitive impairment: a machine learning approach.

The international journal of neuropsychopharmacology
BACKGROUND: The global prevalence of dementia is significantly increasing. Early detection and prevention strategies, particularly for mild cognitive impairment (MCI), are crucial but currently hindered by the lack of established biomarkers. Here, we...

Assessment of Social Robotics for the Enhancement of Cognitive and Physical Functioning in Older Adults.

Studies in health technology and informatics
In the field of elder care, many countries are facing a shortage of nursing staff, which presents a significant challenge that necessitates innovative solutions to support older individuals in nursing homes. This article explores a use case involving...

Epidemiology characteristics and clinical outcomes of composite Hodgkin lymphoma and diffuse large B-cell lymphoma using machine learning.

The oncologist
Composite lymphoma (CL) is rare. We conducted an analysis of 53 329 cases of diffuse large B-cell lymphoma (DLBCL), 17,916 cases of Hodgkin lymphoma (HL), and 869 cases of composite HL and DLBCL from the SEER database diagnosed between 2000 and 2019....

Dynamic and Static Structure-Function Coupling With Machine Learning for the Early Detection of Alzheimer's Disease.

Human brain mapping
The progression of Alzheimer's disease (AD) involves complex changes in brain structure and function that are driven by their interaction, making structure-function coupling (SFC) a valuable indicator for early detection of AD. Static SFC refers to t...

Determining health care cost drivers in older Hodgkin lymphoma survivors using interpretable machine learning methods.

Journal of managed care & specialty pharmacy
BACKGROUND: The cost of health care for patients with Hodgkin lymphoma (HL) is projected to rise, making it essential to understand expenditure drivers across different demographics, including the older adult population. Although older HL patients co...

Evaluating Traditional, Deep Learning and Subfield Methods for Automatically Segmenting the Hippocampus From MRI.

Human brain mapping
Given the relationship between hippocampal atrophy and cognitive impairment in various pathological conditions, hippocampus segmentation from MRI is an important task in neuroimaging. Manual segmentation, though considered the gold standard, is time-...

Prediction of Verbal Abilities From Brain Connectivity Data Across the Lifespan Using a Machine Learning Approach.

Human brain mapping
Compared to nonverbal cognition such as executive or memory functions, language-related cognition generally appears to remain more stable until later in life. Nevertheless, different language-related processes, for example, verbal fluency versus voca...