AIMC Topic: Aged, 80 and over

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Acute myeloid leukemia risk stratification in younger and older patients through transcriptomic machine learning models.

Scientific reports
Acute Myeloid Leukemia (AML) is a genetically and clinically heterogeneous disease that can develop at any age. While AML incidence increases with age and distinct genetic alterations are observed in younger versus older patients, current classificat...

Estimating 10-Year Cardiovascular Disease Risk in Primary Prevention Using UK Electronic Health Records and a Hybrid Multitask BERT Model: Retrospective Cohort Study.

JMIR medical informatics
BACKGROUND: Cardiovascular disease (CVD) remains a leading cause of preventable morbidity and mortality, highlighting the need for early risk stratification in primary prevention. Traditional Cox models assume proportional hazards and linear effects,...

Assessing the accuracy of survival machine learning and traditional statistical models for Alzheimer's disease prediction over time: a study on the ADNI cohort.

BMC medical research methodology
BACKGROUND: Mild cognitive impairment (MCI) represents a transitional stage to Alzheimer's disease (AD), making progression prediction crucial for timely intervention. Predictive models integrating clinical, laboratory, and survival data can enhance ...

Introducing FREM: a decision-support approach for automated identification of individuals at high imminent fracture risk.

Archives of osteoporosis
UNLABELLED: This study used explainable AI to improve the Danish FREM model for predicting one-year risk of major osteoporotic fractures in over 2.4 million individuals aged ≥ 45. A DART boosting algorithm improved performance (AUC 0.77), with explai...

Deep learning-based non-invasive differential diagnosis of eyelid basal cell and sebaceous gland carcinomas using photographic images.

International ophthalmology
PURPOSE: Pathological examination, the current gold standard for differentiating eyelid basal cell carcinoma (BCC) and sebaceous gland carcinoma (SGC), is invasive, time-consuming, and often inaccessible in primary care hospitals. Therefore, a non-in...

Factors contributing to differences in physical activity levels in (pre)frail older adults living in rural areas of China.

PloS one
INTRODUCTION: Physical Activity (PA) is essential for enhancing the physical function of pre-frail and frail older adults. However, among this group, PA-levels vary significantly. Identifying the factors contributing to these differences could suppor...

Machine learning models for risk prediction of age-related macular degeneration in Fujian eye study.

PloS one
OBJECTIVE: Age-related macular degeneration (AMD) is a retinal disorder that significantly impairs vision. This study investigates various machine learning models for predicting AMD risk, laying the groundwork for further research using big data and ...

Deep learning algorithm for predicting rapid progression of abdominal aortic aneurysm by integrating CT images and clinical features.

Scientific reports
Abdominal aortic aneurysm (AAA) progression carries a significant rupture risk, demanding accurate prediction models beyond traditional methods that rely on limited clinical parameters and often overlook complex factor interplay. We aimed to enhance ...

Prognostic Value of AI-Assisted Lesion Tracking on End-of-Treatment PSMA PET in mCRPC Patients Treated with Lu-PSMA: A Retrospective, Single-Center Study.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
This study aimed to explore the prognostic value of the artificial intelligence-assisted lesion tracking applied to prostate-specific membrane antigen (PSMA) PET in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with PS...

[Ga]Ga-PSMA-11 PET Tumor Volume Predicts Overall Survival of Patients with Metastatic Prostate Cancer Undergoing Taxane-Based Chemotherapy.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Prostate-specific membrane antigen (PSMA) PET has the potential to monitor the response to taxane-based chemotherapy in patients with prostate cancer and shows promise for predicting outcomes and improving response evaluation. This retrospective stud...