AIMC Topic: Aged

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AI-driven fusion of multimodal data for Alzheimer's disease biomarker assessment.

Nature communications
Alzheimer's disease (AD) diagnosis hinges on detecting amyloid beta (Aβ) plaques and neurofibrillary tau (τ) tangles, typically assessed using PET imaging. While accurate, these modalities are expensive and not widely accessible, limiting their utili...

Deep learning and radiomics fusion for predicting the invasiveness of lung adenocarcinoma within ground glass nodules.

Scientific reports
Microinvasive adenocarcinoma (MIA) and invasive adenocarcinoma (IAC) require distinct treatment strategies and are associated with different prognoses, underscoring the importance of accurate differentiation. This study aims to develop a predictive m...

Enhancing meningioma tumor classification accuracy through multi-task learning approach and image analysis of MRI images.

PloS one
BACKGROUND: Accurate classification of meningioma brain tumors is crucial for determining the appropriate treatment plan and improving patient outcomes. However, this task is challenging due to the slow-growing nature of these tumors and the potentia...

Prediction of hematoma changes in spontaneous intracerebral hemorrhage using a Transformer-based generative adversarial network to generate follow-up CT images.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
PURPOSE: To visualize and assess hematoma growth trends by generating follow-up CT images within 24 h based on baseline CT images of spontaneous intracerebral hemorrhage (sICH) using Transformer-integrated Generative Adversarial Networks (GAN).

Improving early detection of Alzheimer's disease through MRI slice selection and deep learning techniques.

Scientific reports
Alzheimer's disease is a progressive neurodegenerative disorder marked by cognitive decline, memory loss, and behavioral changes. Early diagnosis, particularly identifying Early Mild Cognitive Impairment (EMCI), is vital for managing the disease and ...

Prediction of cervical cancer lymph node metastasis based on multisequence magnetic resonance imaging radiomics and deep learning features: a dual-center study.

Scientific reports
Cervical cancer is a leading cause of death from malignant tumors in women, and accurate evaluation of occult lymph node metastasis (OLNM) is crucial for optimal treatment. This study aimed to develop several predictive models-including Clinical mode...

Development and validation of a machine learning model for predicting vulnerable carotid plaques using routine blood biomarkers and derived indicators: insights into sex-related risk patterns.

Cardiovascular diabetology
BACKGROUND: Early detection of vulnerable carotid plaques is critical for stroke prevention. This study aimed to develop a machine learning model based on routine blood tests and derived indices to predict plaque vulnerability and assess sex-specific...

Serum peptide biomarkers by MALDI-TOF MS coupled with machine learning for diagnosis and classification of hepato-pancreato-biliary cancers.

Scientific reports
This study aimed to investigate the potential of peptide mass fingerprints (PMFs) of the serum peptidome using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), in combination with machine learning algorithm...

Exploring the feasibility of AI-based analysis of histopathological variability in salivary gland tumours.

Scientific reports
This study uses artificial intelligence (AI) for differentiation between salivary gland tumours (SGT) using digitised Haematoxylin and Eosin stained whole-slide images (WSI). Machine learning (ML) classifiers were developed and tested using 320 scann...

Development and validation of interpretable machine learning models for predicting AKI risk in patients treated with PD-1/PD-L1: a retrospective study.

BMC medical informatics and decision making
BACKGROUND: Anti-programmed cell death protein 1 (PD-1)/programmed cell death ligand 1 (PD-L1) immunotherapy has revolutionized cancer treatment. However, it can cause immune-related adverse events, including acute kidney injury (AKI). Such adverse e...