NPJ primary care respiratory medicine
Nov 20, 2025
OBJECTIVE: This study explored the application of Machine Learning (ML) techniques to cluster patients with suspected sleep apnea (SA), based on clinical-demographic data, with the aim of optimizing diagnostic pathways and enabling more personalized ...
OBJECTIVES: BMI and age are associated with the risk of osteoporosis (OP). The dynamic facial aging process involves changes in skin, muscle, fat, and facial bone structures, with facial skeletal aging affecting facial contours through volumetric red...
BACKGROUND: Transcutaneous transhepatic gallbladder drainage (PTGBD) has shown significant efficacy in the treatment of elderly patients with acute cholecystitis. The goal of this study is to develop a machine learning-based web calculator aimed at p...
Gastric cancer (GC) remains one of the most prevalent and lethal malignancies worldwide, necessitating the development of efficient, non-invasive methods for early detection. In this study, a serum diagnostic approach based on shell-isolated nanopart...
BACKGROUND: Machine learning shows great potential in science but struggles with complex, high-dimensional multi-omics data. PD progression is long, diagnosed mainly by clinical signs. This paper proposes a novel decision fusion method to improve the...
BACKGROUND: Acute Respiratory Distress Syndrome (ARDS) remains a critical condition associated with high mortality rates, prolonged hospitalization, and reduced quality of life despite advances in critical care. The albumin-corrected anion gap (ACAG)...
BACKGROUND: Type 2 diabetes mellitus (T2DM) is a major driver of coronary artery disease (CAD). Prior studies often conflate T2DM- and CAD-specific metabolic alterations, limiting insights into CAD pathogenesis in T2DM. This study aimed to distinguis...
Numerical variations and transitional anatomy in the human vertebral column represent a significant yet understudied aspect of skeletal development with potential effects on multiple physiological systems. Utilising UK Biobank data, we integrated gen...
The cerebellar vermis undergoes diverse structural changes with aging, yet region-specific aging patterns remain underexplored. Using Brain Structure Age (BSA), a deep learning biomarker from structural magnetic resonance imaging (MRI), we aimed to: ...
Early-phase severe complications remain a major cause of morbidity and mortality during induction chemotherapy for acute leukaemia. Existing risk scores capture only limited prognostic variance and are rarely well-calibrated for clinical decision sup...
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