AIMC Topic: Aged

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Scalable Big Data Platform With End-to-End Traceability for Health Data Monitoring in Older Adults: Development and Performance Evaluation.

JMIR medical informatics
BACKGROUND: The increasing use of real-time health data from wearable devices and self-reported questionnaires offers significant opportunities for preventive care in aging populations. However, current health data platforms often lack built-in mecha...

Interpretable multimodal radiopathomics model predicting pathological complete response to neoadjuvant chemoimmunotherapy in esophageal squamous cell carcinoma.

Journal for immunotherapy of cancer
BACKGROUND: Accurate preoperative prediction of pathological complete response (pCR) following neoadjuvant chemoimmunotherapy (nCIT) could help individualize treatment for patients with esophageal squamous cell carcinoma (ESCC). This study aimed to d...

Connectomics in brain tumor surgery: large-scale clinical feasibility and hypothesis-generating tractometry findings.

Journal of neuro-oncology
BACKGROUND: Maximal tumor resection with neurological preservation is central to brain tumor surgery. This study evaluates the integration of an artificial intelligence-based connectomics platform for surgical planning, with exploratory tractometry a...

Application of risk prediction model to evaluate the effect of mechanical ventilation on postoperative pulmonary complications in thoracic surgery.

European journal of medical research
OBJECTIVE: This retrospective cohort study aimed to systematically evaluate the impact of different mechanical ventilation strategies on postoperative pulmonary complications (PPCs) in thoracic surgery and to establish a risk prediction model that fa...

Machine learning-based risk prediction model for cognitive dysfunction in elderly individuals.

PloS one
BACKGROUND: With the advancement of globalization, the prevalence of cognitive dysfunction in the elderly population has risen significantly. Early intervention may dramatically alleviate the disease burden and reduce economic costs associated with c...

Leading predictors and their associations with combination opioid pain therapy in older adults with cancer: Application of machine learning approaches.

PloS one
Combined use of opioids and other pharmacological therapies used for pain management, such as non-steroidal anti-inflammatory drugs (NSAIDs), benzodiazepines, gabapentinoids, and/or skeletal muscle relaxants (SMRs), in older adult cancer survivors ca...

Association between stress hyperglycemia ratio and all-cause mortality in critically ill patients with mitral valve disease.

Scientific reports
The study of stress hyperglycemia ratio (SHR) aims to further investigate the relationship between chronic glucose factors and adverse clinical events, particularly cardiovascular outcomes, in critically ill patients. However, prior research has not ...

A Framework for Identifying Serum Exosomal Lipid Biomarkers in Alzheimer's Disease.

ACS chemical neuroscience
The escalating global burden of Alzheimer's disease (AD), projected to reach $16.9 trillion by 2050 with disproportionate impacts on low- and middle-income countries and racial minorities, underscores an urgent need for accessible early detection too...

Continuous tobacco smoking increases mortality in diffuse large B-cell lymphoma but not follicular lymphoma, a Finnish population-based study.

Acta oncologica (Stockholm, Sweden)
BACKGROUND AND PURPOSE: Tobacco smoking was prognostic in B-cell lymphomas in the pre-rituximab era, but the association with modern treatment, stage, subtypes, and survival outcomes remains unclear. Patient/material and methods: All patients with di...