AIMC Topic: Aged

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Artificial intelligence in neuropathology: deep learning-based assessment of tauopathy.

Laboratory investigation; a journal of technical methods and pathology
Accumulation of abnormal tau in neurofibrillary tangles (NFT) occurs in Alzheimer disease (AD) and a spectrum of tauopathies. These tauopathies have diverse and overlapping morphological phenotypes that obscure classification and quantitative assessm...

Highly accelerated, model-free diffusion tensor MRI reconstruction using neural networks.

Medical physics
PURPOSE: The purpose of this study was to develop a neural network that accurately performs diffusion tensor imaging (DTI) reconstruction from highly accelerated scans.

Random forest prediction of Alzheimer's disease using pairwise selection from time series data.

PloS one
Time-dependent data collected in studies of Alzheimer's disease usually has missing and irregularly sampled data points. For this reason time series methods which assume regular sampling cannot be applied directly to the data without a pre-processing...

Discovering the Type 2 Diabetes in Electronic Health Records Using the Sparse Balanced Support Vector Machine.

IEEE journal of biomedical and health informatics
The diagnosis of type 2 diabetes (T2D) at an early stage has a key role for an adequate T2D integrated management system and patient's follow-up. Recent years have witnessed an increasing amount of available electronic health record (EHR) data and ma...

SALMANTICOR study. Rationale and design of a population-based study to identify structural heart disease abnormalities: a spatial and machine learning analysis.

BMJ open
INTRODUCTION: This study aims to obtain data on the prevalence and incidence of structural heart disease in a population setting and, to analyse and present those data on the application of spatial and machine learning methods that, although known to...

Differentiating kidney stones from phleboliths in unenhanced low-dose computed tomography using radiomics and machine learning.

European radiology
OBJECTIVES: Distinguishing between kidney stones and phleboliths can constitute a diagnostic challenge in patients undergoing unenhanced low-dose CT (LDCT) for acute flank pain. We sought to investigate the accuracy of radiomics and a machine-learnin...

DeepSOFA: A Continuous Acuity Score for Critically Ill Patients using Clinically Interpretable Deep Learning.

Scientific reports
Traditional methods for assessing illness severity and predicting in-hospital mortality among critically ill patients require time-consuming, error-prone calculations using static variable thresholds. These methods do not capitalize on the emerging a...

New-Onset Alzheimer's Disease and Normal Subjects 100% Differentiated by P300.

American journal of Alzheimer's disease and other dementias
Previous work has suggested that evoked potential analysis might allow the detection of subjects with new-onset Alzheimer's disease, which would be useful clinically and personally. Here, it is described how subjects with new-onset Alzheimer's diseas...