AIMC Topic: Aging

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Determinants of Chromatin Organization in Aging and Cancer-Emerging Opportunities for Epigenetic Therapies and AI Technology.

Genes
This review article critically examines the pivotal role of chromatin organization in gene regulation, cellular differentiation, disease progression and aging. It explores the dynamic between the euchromatin and heterochromatin, coded by a complex ar...

Identification of key genes and biological pathways associated with vascular aging in diabetes based on bioinformatics and machine learning.

Aging
Vascular aging exacerbates diabetes-associated vascular damage, a major cause of microvascular and macrovascular complications. This study aimed to elucidate key genes and pathways underlying vascular aging in diabetes using integrated bioinformatics...

nBEST: Deep-learning-based non-human primates Brain Extraction and Segmentation Toolbox across ages, sites and species.

NeuroImage
Accurate processing and analysis of non-human primate (NHP) brain magnetic resonance imaging (MRI) serves an indispensable role in understanding brain evolution, development, aging, and diseases. Despite the accumulation of diverse NHP brain MRI data...

A ResNet mini architecture for brain age prediction.

Scientific reports
The brain presents age-related structural and functional changes in the human life, with different extends between subjects and groups. Brain age prediction can be used to evaluate the development and aging of human brain, as well as providing valuab...

The effect of head motion on brain age prediction using deep convolutional neural networks.

NeuroImage
Deep learning can be used effectively to predict participants' age from brain magnetic resonance imaging (MRI) data, and a growing body of evidence suggests that the difference between predicted and chronological age-referred to as brain-predicted ag...

Predicting the age of field mosquitoes using mass spectrometry and deep learning.

Science advances
Mosquito-borne diseases like malaria are rising globally, and improved mosquito vector surveillance is needed. Survival of mosquitoes is key for epidemiological monitoring of malaria transmission and evaluation of vector control strategies targeting...

AI, ageing and brain-work productivity: Technological change in professional Japanese chess.

PloS one
Using Japanese professional chess (Shogi) players' records in the setting where various external factors are controlled in deterministic and finite games, this paper examines how and the extent to which the emergence of technological changes influenc...

A machine-learning method isolating changes in wrist kinematics that identify age-related changes in arm movement.

Scientific reports
Normal aging often results in an increase in physiological tremors and slowing of the movement of the hands, which can impair daily activities and quality of life. This study, using lightweight wearable non-invasive sensors, aimed to detect and ident...