AIMC Topic: Algorithms

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Boosted feature selectors: a case study on prediction P-gp inhibitors and substrates.

Journal of computer-aided molecular design
Feature selection is commonly used as a preprocessing step to machine learning for improving learning performance, lowering computational complexity and facilitating model interpretation. This paper proposes the application of boosting feature select...

Representations of regular and irregular shapes by deep Convolutional Neural Networks, monkey inferotemporal neurons and human judgments.

PLoS computational biology
Recent studies suggest that deep Convolutional Neural Network (CNN) models show higher representational similarity, compared to any other existing object recognition models, with macaque inferior temporal (IT) cortical responses, human ventral stream...

Fixed-time synchronization of inertial memristor-based neural networks with discrete delay.

Neural networks : the official journal of the International Neural Network Society
This paper is concerned with the fixed-time synchronization control of inertial memristor-based neural networks with discrete delay. We design four different kinds of feedback controllers, under which the considered inertial memristor-based neural ne...

Identification of Novel Genes in Human Airway Epithelial Cells associated with Chronic Obstructive Pulmonary Disease (COPD) using Machine-Based Learning Algorithms.

Scientific reports
The aim of this project was to identify candidate novel therapeutic targets to facilitate the treatment of COPD using machine-based learning (ML) algorithms and penalized regression models. In this study, 59 healthy smokers, 53 healthy non-smokers an...

DeepFocus: Detection of out-of-focus regions in whole slide digital images using deep learning.

PloS one
The development of whole slide scanners has revolutionized the field of digital pathology. Unfortunately, whole slide scanners often produce images with out-of-focus/blurry areas that limit the amount of tissue available for a pathologist to make acc...

Heterogeneous Domain Adaptation for IHC Classification of Breast Cancer Subtypes.

IEEE/ACM transactions on computational biology and bioinformatics
Increasingly, multiple parallel omics datasets are collected from biological samples. Integrating these datasets for classification is an open area of research. Additionally, whilst multiple datasets may be available for the training samples, future ...

Novel computer-assisted diagnosis system for endoscopic disease activity in patients with ulcerative colitis.

Gastrointestinal endoscopy
BACKGROUND AND AIMS: Evaluation of endoscopic disease activity for patients with ulcerative colitis (UC) is important when determining the treatment of choice. However, endoscopists require a certain period of training to evaluate the activity of inf...

JOURNAL CLUB: Use of Gradient Boosting Machine Learning to Predict Patient Outcome in Acute Ischemic Stroke on the Basis of Imaging, Demographic, and Clinical Information.

AJR. American journal of roentgenology
OBJECTIVE: When treatment decisions are being made for patients with acute ischemic stroke, timely and accurate outcome prediction plays an important role. The optimal rehabilitation strategy also relies on long-term outcome predictions. The decision...

Using clinical Natural Language Processing for health outcomes research: Overview and actionable suggestions for future advances.

Journal of biomedical informatics
The importance of incorporating Natural Language Processing (NLP) methods in clinical informatics research has been increasingly recognized over the past years, and has led to transformative advances. Typically, clinical NLP systems are developed and...