AIMC Topic: Algorithms

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Imitating the respiratory activity of the brain stem by using artificial neural networks: exploratory study on an animal model of lactic acidosis and proof of concept.

Journal of clinical monitoring and computing
Artificial neural networks (ANNs) are versatile tools capable of learning without prior knowledge. This study aims to evaluate whether ANN can calculate minute volume during spontaneous breathing after being trained using data from an animal model of...

Physically informed deep neural networks for metabolite-corrected plasma input function estimation in dynamic PET imaging.

Computer methods and programs in biomedicine
INTRODUCTION: We propose a novel approach for the non-invasive quantification of dynamic PET imaging data, focusing on the arterial input function (AIF) without the need for invasive arterial cannulation.

Automated Bio-AFM Generation of Large Mechanome Data Set and Their Analysis by Machine Learning to Classify Cancerous Cell Lines.

ACS applied materials & interfaces
Mechanobiological measurements have the potential to discriminate healthy cells from pathological cells. However, a technology frequently used to measure these properties, i.e., atomic force microscopy (AFM), suffers from its low output and lack of s...

An Unsupervised Learning Tool for Plaque Tissue Characterization in Histopathological Images.

Sensors (Basel, Switzerland)
Stroke is the second leading cause of death and a major cause of disability around the world, and the development of atherosclerotic plaques in the carotid arteries is generally considered the leading cause of severe cerebrovascular events. In recent...

Acquisition of Data on Kinematic Responses to Unpredictable Gait Perturbations: Collection and Quality Assurance of Data for Use in Machine Learning Algorithms for (Near-)Fall Detection.

Sensors (Basel, Switzerland)
Slip, trip, and fall (STF) accidents cause high rates of absence from work in many companies. During the 2022 reporting period, the German Social Accident Insurance recorded 165,420 STF accidents, of which 12 were fatal and 2485 led to disability pen...

NABNet: Deep Learning-Based IoT Alert System for Detection of Abnormal Neck Behavior.

Sensors (Basel, Switzerland)
The excessive use of electronic devices for prolonged periods has led to problems such as neck pain and pressure injury in sedentary people. If not detected and corrected early, these issues can cause serious risks to physical health. Detectors for g...

MASDF-Net: A Multi-Attention Codec Network with Selective and Dynamic Fusion for Skin Lesion Segmentation.

Sensors (Basel, Switzerland)
Automated segmentation algorithms for dermoscopic images serve as effective tools that assist dermatologists in clinical diagnosis. While existing deep learning-based skin lesion segmentation algorithms have achieved certain success, challenges remai...

Machine learning model for non-alcoholic steatohepatitis diagnosis based on ultrasound radiomics.

BMC medical imaging
BACKGROUND: Non-Alcoholic Steatohepatitis (NASH) is a crucial stage in the progression of Non-Alcoholic Fatty Liver Disease(NAFLD). The purpose of this study is to explore the clinical value of ultrasound features and radiological analysis in predict...

Benchmarking robustness of deep neural networks in semantic segmentation of fluorescence microscopy images.

BMC bioinformatics
BACKGROUND: Fluorescence microscopy (FM) is an important and widely adopted biological imaging technique. Segmentation is often the first step in quantitative analysis of FM images. Deep neural networks (DNNs) have become the state-of-the-art tools f...

Holistic in silico developability assessment of novel classes of small proteins using publicly available sequence-based predictors.

Journal of computer-aided molecular design
The development of novel therapeutic proteins is a lengthy and costly process, with an average attrition rate of 91% (Thomas et al. Clinical Development Success Rates and Contributing Factors 2011-2020, 2021). To increase the probability of success a...