Drug registration requires risk assessment of new active pharmaceutical ingredients or excipients to ensure they are safe for human health and the environment. However, traditional risk assessment is expensive and relies heavily on animal testing. Ma...
Dead on arrival (DOA) refers to animals, particularly poultry, that die during the pre-slaughter phase. Elevated rates of DOA frequently signify substandard welfare conditions and might stem from multiple causes, resulting in diminished productivity ...
This in vitro study aimed to quantify the penetration of hydrogen peroxide (HP), bleaching efficacy (BE) and toxicity in larvae in different bleaching techniques using 6% HP. Sixty maxillary premolars were divided in six groups (n = 10): Pola Luminat...
Sepsis is a clinical syndrome resulting from the interaction between coagulation, inflammation, immunity and other systems. Coagulation activation is an initial factor for sepsis to develop into multiple organ dysfunction. Therefore, anticoagulant th...
Neural networks : the official journal of the International Neural Network Society
Dec 5, 2024
The spike-based neuronal responses within the ventral intraparietal area (VIP) exhibit intricate spatial and temporal dynamics in the posterior parietal cortex, presenting decoding challenges such as limited data availability at the biological popula...
Piezoelectric micro-robots have gained considerable attention in rescue and medical applications due to their rapid response times and high positioning accuracy. In this paper, inspired by the human butterfly locomotion pattern, we propose a novel re...
International journal of antimicrobial agents
Dec 5, 2024
BACKGROUND: Given the rising number of multidrug-resistant (MDR) bacteria, there is a need to design synthetic antimicrobial peptides (AMPs) that are highly active, non-hemolytic, and highly soluble. Machine learning tools allow the straightforward i...
Cell communication and signaling : CCS
Dec 5, 2024
BACKGROUND: Epidermal growth factor receptor (EGFR) T790M mutation often occurs during long durational erlotinib treatment of non-small cell lung cancer (NSCLC) patients, leading to drug resistance and disease progression. Identification of new selec...
Our algorithmic understanding of vision has been revolutionized by a reverse engineering paradigm that involves building artificial systems that perform the same tasks as biological systems. Here, we extend this paradigm to social behavior. We embodi...
This study addresses the challenge of predicting Dalbulus maidis (DeLong & Wolcott) (Hemiptera: Cicadellidae) density in cornfields by developing an artificial neural network (ANN). Over two years, we collected data on meteorological variables (atmos...
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