Journal of controlled release : official journal of the Controlled Release Society
Sep 10, 2025
As three-dimensional (3D), physiologically relevant models, organoids are rapidly becoming revolutionary platforms in biomedical research. With their ability to recapitulate tissue architecture, disease heterogeneity, and patient-specific therapeutic...
The fruit fly Anastrepha fraterculus (Wiedemann) (Diptera: Tephritidae) is one of the main pests in apple orchards. Artificial neural networks (ANNs) are tools with good ability to predict phenomena such as the seasonal dynamics of pest populations. ...
Snakebite envenoming is a neglected tropical disease that affects mainly rural populations, where antivenom is scarce. Understanding environmental drivers of snakebite incidence is critical for public health preparedness. This study employs causal in...
Pollination is essential for maintaining biodiversity and ensuring food security, and in Europe it is primarily mediated by four insect orders (Coleoptera, Diptera, Hymenoptera, Lepidoptera). However, traditional monitoring methods are costly and tim...
Probabilistic Random Forest is an extension of the traditional Random Forest machine learning algorithm that is one of the frequently used machine learning algorithms employed for species distribution modeling. However, with the use of complex datase...
Research over the last 20 years has shed important light on the vocal behaviour of our closest living relatives, bonobos and chimpanzees, but mostly relies on qualitative vocal repertoires, for which quantitative validations are absent. Such data are...
OBJECTIVES: Small animal models, particularly mice, are crucial for studying gastrointestinal diseases like colorectal cancer. Tumor assessment via colonoscopy generates large video datasets, necessitating automated analysis due to limited resources ...
This study investigated the metabolomic transformation of sea buckthorn milk fermented by Lactiplantibacillus plantarum to identify novel bioactive compounds and improve both nutritional and sensory attributes. An untargeted metabolomics workflow int...
Biogenic amines (BAs) are critical indicators of spoilage in aquatic products, but conventional detection methods are destructive and inefficient. This study proposes a nondestructive approach combining near-infrared (NIR) spectroscopy with deep lear...
Crohn's disease (CD) is a chronic inflammatory bowel condition that significantly impairs patients' quality of life. With no cure currently available, the need to discover novel biomarkers and develop effective therapeutic strategies is paramount. Th...
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