AIMC Topic: Animals

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Uncovering injury-specific proteomic signatures and neurodegenerative risks in single and repetitive traumatic brain injury.

Signal transduction and targeted therapy
Traumatic brain injury (TBI) is a major public health concern associated with an increased risk of neurodegenerative diseases including Alzheimer's disease (AD), Parkinson's disease (PD), and chronic traumatic encephalopathy, yet the underlying molec...

Advances in vaccine adjuvant development and future perspectives.

Drug delivery
Use of highly purified antigens to improve vaccine safety has led to reduced immunogenicity and efficacy, resulting in the need for adjuvants to increase and/or modulate the immunogenicity of the vaccine. Despite the need for potent and safe vaccine ...

Bio-inspired swarm of underwater robots: a review.

Bioinspiration & biomimetics
With the in-depth integration of research across multiple disciplines, such as biomimetics, robotics, and sensing technology, significant advancements have been made in swarm robotics technology, which has been applied in areas including drone swarms...

Self-assembling peptide hydrogels: design, mechanisms, characterization, and biomedical applications.

Soft matter
Self-assembled peptide hydrogels have emerged as a research frontier in biomedical engineering due to their exceptional water-retention capacity and spatiotemporal drug release kinetics. Researchers can fabricate biomaterials with customizable struct...

Combinatorial discovery of microtopographical landscapes that resist biofilm formation through quorum sensing mediated autolubrication.

Nature communications
Bio-instructive materials that intrinsically inhibit biofilm formation have significant anti-biofouling potential in industrial and healthcare settings. Since bacterial surface attachment is sensitive to surface topography, we experimentally surveyed...

Microglial pruning of glycinergic synapses disinhibits spinal PKCγ interneurons to drive pain hypersensitivity in mice.

Science translational medicine
Microglial activation is linked to neuroinflammation in neuropathic pain. Recently, microglia-mediated synaptic pruning has received mounting attention. However, the exact role of spinal microglia in modulating neuropathic pain-associated neural circ...

Bio-inspired robotics in times of ecological crisis: an attempt at self-criticism.

Bioinspiration & biomimetics
This article attempts to show that current trends in bio-inspired robotics research are incompatible with the transformations needed to address the current ecological crisis. A large part of the scientific community takes refuge behind short-term cha...

Chemical imaging for biological systems: techniques, AI-driven processing, and applications.

Journal of materials chemistry. B
Visualizing the chemical compositions of biological samples is pivotal to advancing biological sciences, with the past two decades witnessing the emergence of innovative chemical imaging platforms such as single-molecule imaging, coherent Raman scatt...

Incorporating sparse labels into hidden Markov models using weighted likelihoods improves accuracy and interpretability in biologging studies.

PloS one
Ecologists often use a hidden Markov model to decode a latent process, such as a sequence of an animal's behaviours, from an observed biologging time series. Modern technological devices such as video recorders and drones now allow researchers to dir...

Morphological traits and machine learning for genetic lineage prediction of two reef-building corals.

PloS one
Integrating multiple lines of evidence that support molecular taxonomy analysis has proven to be a robust method for species delimitation in scleractinian corals. However, morphology often conflicts with genetic approaches due to high phenotypic plas...