Status epilepticus (SE), seizures lasting beyond five minutes, is a medical emergency commonly treated with benzodiazepines which enhance GABA receptor (GABAR) conductance. Despite widespread use, benzodiazepines fail in over one-third of patients, p...
Animal growth is driven by the collective actions of cells, which are reciprocally influenced in real-time by the animal's overall growth state. Whereas cell behavior and animal growth state are expected to be tightly coupled, it is not yet determine...
Wnt signaling is important in embryonic development and tumorigenesis. These biological effects can be exerted by the activation of the β-catenin-dependent canonical pathway or the β-catenin-independent non-canonical pathway. DKK1 is a potent inhibit...
INTRODUCTION: Microtubules, composing of α, β-tubulin dimers, are important for cellular processes like proliferation and transport, thereby they become suitable targets for research in cancer. Existing candidates often exhibit off-target effects, ne...
Refractory epilepsy is an intractable neurological disorder that can be associated with oligogenic/polygenic etiologies. Through trio-based whole-exome sequencing analysis, we identified a clinical case of refractory epilepsy with three candidate gen...
The Japanese quail (Coturnix japonica) is an increasingly popular species in poultry production. Concern about poultry welfare, including quail, has resulted in a stronger focus for farms to transition to cage-free housing as highlighted by the 2020 ...
IEEE transactions on ultrasonics, ferroelectrics, and frequency control
Aug 1, 2025
Ultrasound localization microscopy (ULM) has revolutionized microvascular imaging by breaking the acoustic diffraction limit. However, different ULM workflows depend heavily on distinct prior knowledge, such as the impulse response and empirical sele...
Antimicrobial peptides (AMPs) are small molecular peptides that widely exist in organisms to resist external microbial invasion and play a crucial role in the host's immune defense system. Owing to their functions of efficient broad-spectrum killing ...
Propagation-based imaging (one method of X-ray phase contrast imaging) with microcomputed tomography (PBI-µCT) offers the potential to visualise low-density materials, such as soft tissues and hydrogel constructs, which are difficult to be identified...
The increasing global reliance on aquaculture is challenged by disease outbreaks, exacerbated by antibiotic resistance, and environmental stressors. Traditional strategies, such as antibiotic treatments and chemical interventions, are becoming less e...
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