AIMC Topic: Animals

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Identifying the DNA methylation preference of transcription factors using ProtBERT and SVM.

PLoS computational biology
Transcription factors (TFs) can affect gene expression by binding to certain specific DNA sequences. This binding process of TFs may be modulated by DNA methylation. A subset of TFs that serve as methylation readers preferentially binds to certain me...

Deep Eutectic Solvent Extraction Assisted Ligand Affinity Assay for α-Glucosidase Inhibitors Screening From the Plasma of Rats Administrated Pueraria lobata Extracts.

Journal of separation science
In this work, for the first time, a deep eutectic solvent assisted ligand affinity assay was proposed. Several critical parameters affecting the analysis performance were investigated and the optimized DES extract conditions were as follows: the solu...

Amelioration of Chronic Ethanol Administration-Induced Learning and Memory Impairments by High-Intensity Interval Training (HIIT) and Ritalin.

Brain and behavior
OBJECTIVES: The current study aimed to investigate the impacts of 8-week high-intensity interval training (HIIT) and Ritalin (RIT), alone and in combination, on cognitive functions and hippocampal oxidative parameters following chronic ethanol consum...

Exploring community knowledge, perceptions, and the impacts of anthrax among farming communities living in game management areas in Zambia: A qualitative study using a hybrid approach.

PLoS neglected tropical diseases
Anthrax remains a neglected zoonotic disease of critical public and animal health significance in Zambia, particularly in regions with active human-wildlife-livestock interfaces such as the Western, Southern and Eastern provinces of Zambia. This stud...

A classification-occupancy model based on automatically identified species data.

Ecology
Occupancy models estimate a species' occupancy probability while accounting for imperfect detection, but often overlook the issue of false-positive detections. This problem of false positives has gained attention recently with the rapid advancement o...

Inside a Metastatic Fracture: Molecular Bases and New Potential Therapeutic Targets.

Cancer medicine
INTRODUCTION: Bone metastases and pathological fractures significantly impact the prognosis and quality of life in cancer patients. However, clinical and radiological features alone have been shown to fail to predict skeletal related events of a bone...

Artificial intelligence to predict inhibitors of drug-metabolizing enzymes and transporters for safer drug design.

Expert opinion on drug discovery
INTRODUCTION: Drug-metabolizing enzymes (DMEs) and transporters (DTs) play integral roles in drug metabolism and drug-drug interactions (DDIs) which directly impact drug efficacy and safety. It is well-established that inhibition of DMEs and DTs ofte...

Applications and Considerations of Artificial Intelligence in Veterinary Sciences: A Narrative Review.

Veterinary medicine and science
In recent years, artificial intelligence (AI) has brought about a significant transformation in healthcare, streamlining manual tasks and allowing professionals to focus on critical responsibilities while AI handles complex procedures. This shift is ...

Comprehensive Global Analysis of Future Trends in Artificial Intelligence-Assisted Veterinary Medicine.

Veterinary medicine and science
BACKGROUND: This study conducts a bibliometric analysis of global trends in 'artificial intelligence studies in veterinary medicine'. The analysis aims to summarise the publications of researchers from various disciplines related to artificial intell...

Investigating the Limits of Familiarity-Based Navigation.

Artificial life
Insect-inspired navigation strategies have the potential to unlock robotic navigation in power-constrained scenarios, as they can function effectively with limited computational resources. One such strategy, familiarity-based navigation, has successf...